2ar8

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Template:STRUCTURE 2ar8

The structure of tryptophan 7-halogenase (PrnA)suggests a mechanism for regioselective chlorination

Template:ABSTRACT PUBMED 16195462

About this Structure

2ar8 is a 1 chain structure with sequence from Pseudomonas fluorescens. Full crystallographic information is available from OCA.

Reference

  • Dong C, Flecks S, Unversucht S, Haupt C, van Pee KH, Naismith JH. Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination. Science. 2005 Sep 30;309(5744):2216-9. PMID:16195462 doi:309/5744/2216
  • Dong C, Kotzsch A, Dorward M, van Pee KH, Naismith JH. Crystallization and X-ray diffraction of a halogenating enzyme, tryptophan 7-halogenase, from Pseudomonas fluorescens. Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1438-40. Epub 2004, Jul 21. PMID:15272170 doi:10.1107/S0907444904012521

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