2j4g
From Proteopedia
(Difference between revisions)
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[[Image:2j4g.png|left|200px]] | [[Image:2j4g.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2j4g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J4G OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:17227027</ref><references group="xtra"/> | + | <ref group="xtra">PMID:17227027</ref><ref group="xtra">PMID:16565725</ref><references group="xtra"/> |
[[Category: Bacteroides thetaiotaomicron]] | [[Category: Bacteroides thetaiotaomicron]] | ||
[[Category: Beta-N-acetylhexosaminidase]] | [[Category: Beta-N-acetylhexosaminidase]] | ||
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[[Category: O-glcnacase]] | [[Category: O-glcnacase]] | ||
[[Category: Thiazoline]] | [[Category: Thiazoline]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:06:44 2009'' | ||
Revision as of 22:06, 14 March 2011
BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR
Template:ABSTRACT PUBMED 17227027
About this Structure
2j4g is a 2 chain structure with sequence from Bacteroides thetaiotaomicron. Full crystallographic information is available from OCA.
Reference
- Whitworth GE, Macauley MS, Stubbs KA, Dennis RJ, Taylor EJ, Davies GJ, Greig IR, Vocadlo DJ. Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise. J Am Chem Soc. 2007 Jan 24;129(3):635-44. PMID:17227027 doi:http://dx.doi.org/10.1021/ja065697o
- Dennis RJ, Taylor EJ, Macauley MS, Stubbs KA, Turkenburg JP, Hart SJ, Black GN, Vocadlo DJ, Davies GJ. Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity. Nat Struct Mol Biol. 2006 Apr;13(4):365-71. Epub 2006 Mar 26. PMID:16565725 doi:http://dx.doi.org/10.1038/nsmb1079
