3kxg

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Revision as of 22:16, 14 March 2011

Template:STRUCTURE 3kxg

Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)

Template:ABSTRACT PUBMED 16298300

About this Structure

3kxg is a 1 chain structure with sequence from Zea mays. Full crystallographic information is available from OCA.

Reference

  • Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA. Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem Biol. 2005 Nov;12(11):1211-9. PMID:16298300 doi:10.1016/j.chembiol.2005.08.015
  • Battistutta R, Mazzorana M, Cendron L, Bortolato A, Sarno S, Kazimierczuk Z, Zanotti G, Moro S, Pinna LA. The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules. Chembiochem. 2007 Oct 15;8(15):1804-9. PMID:17768728 doi:10.1002/cbic.200700307

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