1szm
From Proteopedia
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[[Image:1szm.png|left|200px]] | [[Image:1szm.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1szm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZM OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Selectivity]] | [[Category: Selectivity]] | ||
[[Category: Surrogate kinase]] | [[Category: Surrogate kinase]] | ||
| + | [[Category: Transferase]] | ||
[[Category: X-ray structure]] | [[Category: X-ray structure]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:29:26 2009'' | ||
Revision as of 22:26, 14 March 2011
DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA)
Template:ABSTRACT PUBMED 14996846
About this Structure
1szm is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Gassel M, Breitenlechner CB, Konig N, Huber R, Engh RA, Bossemeyer D. The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. J Biol Chem. 2004 May 28;279(22):23679-90. Epub 2004 Mar 1. PMID:14996846 doi:10.1074/jbc.M314082200
- Prade L, Engh RA, Girod A, Kinzel V, Huber R, Bossemeyer D. Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure. 1997 Dec 15;5(12):1627-37. PMID:9438863
Categories: Bos taurus | Non-specific serine/threonine protein kinase | Bossemeyer, D. | Breitenlechner, C B. | Engh, R A. | Gassel, M. | Huber, R. | Koenig, N. | Amino acid residue exchange | Bisindolyl maleimide 2 | Ly333531 | Pka | Pkc | Selectivity | Surrogate kinase | Transferase | X-ray structure
