2af9

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{{Seed}}
 
[[Image:2af9.png|left|200px]]
[[Image:2af9.png|left|200px]]
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{{ABSTRACT_PUBMED_16216074}}
{{ABSTRACT_PUBMED_16216074}}
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==Disease==
 
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Known disease associated with this structure: GM2-gangliosidosis, AB variant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=272750 272750]]
 
==About this Structure==
==About this Structure==
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2AF9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AF9 OCA].
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[[2af9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AF9 OCA].
==Reference==
==Reference==
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[[Category: Wright, C S.]]
[[Category: Wright, C S.]]
[[Category: Lipid acyl chain stacking]]
[[Category: Lipid acyl chain stacking]]
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[[Category: Lipid binding protein]]
[[Category: Lipid-protein complex]]
[[Category: Lipid-protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:39:54 2009''
 

Revision as of 22:28, 14 March 2011

Template:STRUCTURE 2af9

Crystal Structure analysis of GM2-Activator protein complexed with phosphatidylcholine

Template:ABSTRACT PUBMED 16216074

About this Structure

2af9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wright CS, Mi LZ, Lee S, Rastinejad F. Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity. Biochemistry. 2005 Oct 18;44(41):13510-21. PMID:16216074 doi:http://dx.doi.org/10.1021/bi050668w
  • Wright CS, Li SC, Rastinejad F. Crystal structure of human GM2-activator protein with a novel beta-cup topology. J Mol Biol. 2000 Dec 1;304(3):411-22. PMID:11090283 doi:http://dx.doi.org/10.1006/jmbi.2000.4225
  • Wright CS, Zhao Q, Rastinejad F. Structural analysis of lipid complexes of GM2-activator protein. J Mol Biol. 2003 Aug 22;331(4):951-64. PMID:12909021

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