2gmx
From Proteopedia
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[[Image:2gmx.png|left|200px]] | [[Image:2gmx.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2gmx]] is a 4 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GMX OCA]. | |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Jnk1]] | [[Category: Jnk1]] | ||
[[Category: Protein kinase jnk1 inhibitor]] | [[Category: Protein kinase jnk1 inhibitor]] | ||
| - | + | [[Category: Transcription]] | |
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Revision as of 22:35, 14 March 2011
Contents |
Selective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activity
Template:ABSTRACT PUBMED 16759099
About this Structure
2gmx is a 4 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Szczepankiewicz BG, Kosogof C, Nelson LT, Liu G, Liu B, Zhao H, Serby MD, Xin Z, Liu M, Gum RJ, Haasch DL, Wang S, Clampit JE, Johnson EF, Lubben TH, Stashko MA, Olejniczak ET, Sun C, Dorwin SA, Haskins K, Abad-Zapatero C, Fry EH, Hutchins CW, Sham HL, Rondinone CM, Trevillyan JM. Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80. PMID:16759099 doi:http://dx.doi.org/10.1021/jm060199b
- Liu M, Xin Z, Clampit JE, Wang S, Gum RJ, Haasch DL, Trevillyan JM, Abad-Zapatero C, Fry EH, Sham HL, Liu G. Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors. Bioorg Med Chem Lett. 2006 May 15;16(10):2590-4. Epub 2006 Mar 9. PMID:16527482 doi:http://dx.doi.org/10.1016/j.bmcl.2006.02.046
