2nm1
From Proteopedia
(Difference between revisions)
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[[Image:2nm1.png|left|200px]] | [[Image:2nm1.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2nm1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NM1 OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Rummel, A.]] | [[Category: Rummel, A.]] | ||
[[Category: Botulism]] | [[Category: Botulism]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Neurotransmission]] | [[Category: Neurotransmission]] | ||
[[Category: Synaptotagmin]] | [[Category: Synaptotagmin]] | ||
| - | + | [[Category: Toxin]] | |
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Revision as of 22:36, 14 March 2011
Structure of BoNT/B in complex with its protein receptor
Template:ABSTRACT PUBMED 17167421
About this Structure
2nm1 is a 2 chain structure with sequence from Clostridium botulinum and Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Jin R, Rummel A, Binz T, Brunger AT. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity. Nature. 2006 Dec 21;444(7122):1092-5. Epub 2006 Dec 13. PMID:17167421 doi:http://dx.doi.org/10.1038/nature05387
- Swaminathan S, Eswaramoorthy S. Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B. Nat Struct Biol. 2000 Aug;7(8):693-9. PMID:10932256
- Jayaraman S, Eswaramoorthy S, Ahmed SA, Smith LA, Swaminathan S. N-terminal helix reorients in recombinant C-fragment of Clostridium botulinum type B. Biochem Biophys Res Commun. 2005 Apr 29;330(1):97-103. PMID:15781237 doi:http://dx.doi.org/10.1016/j.bbrc.2005.02.123
