2hx3
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2hx3]] is a 2 chain structure of [[Nitric Oxide Synthase (Part II)]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Nitric Oxide Synthase (Part II)]] | ||
==Reference== | ==Reference== | ||
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[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Nitric oxide synthase]] | [[Category: Nitric oxide synthase]] | ||
| - | + | [[Category: Oxidoreductase]] | |
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Revision as of 23:08, 14 March 2011
Contents |
Rat nNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine
Template:ABSTRACT PUBMED 17425297
About this Structure
2hx3 is a 2 chain structure of Nitric Oxide Synthase (Part II) with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Seo J, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water. J Med Chem. 2007 May 3;50(9):2089-99. Epub 2007 Apr 11. PMID:17425297 doi:10.1021/jm061305c
- Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gomez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat Struct Mol Biol. 2004 Jan;11(1):54-9. Epub 2003 Dec 29. PMID:14718923 doi:http://dx.doi.org/10.1038/nsmb704
