1uz1

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Revision as of 23:59, 14 March 2011

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Template:STRUCTURE 1uz1

FAMILY 1 B-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ISOFAGOMINE LACTAM

About this Structure

1uz1 is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

Reference

• Vincent F, Gloster TM, Macdonald J, Morland C, Stick RV, Dias FM, Prates JA, Fontes CM, Gilbert HJ, Davies GJ. Common inhibition of both beta-glucosidases and beta-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis. Chembiochem. 2004 Nov 5;5(11):1596-9. PMID:15515081 doi:10.1002/cbic.200400169
• Gloster TM, Meloncelli P, Stick RV, Zechel D, Vasella A, Davies GJ. Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics. J Am Chem Soc. 2007 Feb 28;129(8):2345-54. Epub 2007 Feb 6. PMID:17279749 doi:http://dx.doi.org/10.1021/ja066961g