3hs4
From Proteopedia
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{{ABSTRACT_PUBMED_19851004}} | {{ABSTRACT_PUBMED_19851004}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3hs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HS4 OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Polymorphism]] | [[Category: Polymorphism]] | ||
[[Category: Zinc]] | [[Category: Zinc]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 15:09:52 2009'' | ||
Revision as of 00:07, 15 March 2011
Human carbonic anhydrase II complexed with acetazolamide
Template:ABSTRACT PUBMED 19851004
About this Structure
3hs4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sippel KH, Robbins AH, Domsic J, Genis C, Agbandje-McKenna M, McKenna R. High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt, 10):992-5. Epub 2009 Sep 25. PMID:19851004 doi:10.1107/S1744309109036665
- Vidgren J, Liljas A, Walker NP. Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 A. Int J Biol Macromol. 1990 Dec;12(6):342-4. PMID:2128470
Categories: Carbonate dehydratase | Homo sapiens | Agbandje-McKenna, M. | Domsic, J. | Genis, C. | McKenna, R. | Robbins, A H. | Sippel, K H. | 4-thiadiazole-2-sulfonamide | 5-acetamido-1 | Acetazolamide | Acetylation | Ca 2 | Ca ii | Carbonic anhydrase 2 | Carbonic anhydrase ii | Cytoplasm | Disease mutation | Lyase | Metal-binding | Polymorphism | Zinc
