1un4

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Image:1un4.png

Template:STRUCTURE 1un4

CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T80A

Template:ABSTRACT PUBMED 14756559

About this Structure

1un4 is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1h0e. Full crystallographic information is available from OCA.

Reference

  • Holloway DE, Chavali GB, Hares MC, Baker MD, Subbarao GV, Shapiro R, Acharya KR. Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41. Biochemistry. 2004 Feb 10;43(5):1230-41. PMID:14756559 doi:10.1021/bi035654+
  • Leonidas DD, Shapiro R, Allen SC, Subbarao GV, Veluraja K, Acharya KR. Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J Mol Biol. 1999 Jan 22;285(3):1209-33. PMID:9918722 doi:10.1006/jmbi.1998.2378
  • Shapiro R. Structural features that determine the enzymatic potency and specificity of human angiogenin: threonine-80 and residues 58-70 and 116-123. Biochemistry. 1998 May 12;37(19):6847-56. PMID:9578571 doi:10.1021/bi9800146

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OCA

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