2qx1
From Proteopedia
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[[Image:2qx1.png|left|200px]] | [[Image:2qx1.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2qx1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QX1 OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Structural basis for substrate specificity]] | [[Category: Structural basis for substrate specificity]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:10:35 2009'' | ||
Revision as of 00:24, 15 March 2011
Crystal structure of the complex between mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FABH) and decyl-COA disulfide
Template:ABSTRACT PUBMED 18096200
About this Structure
2qx1 is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Sachdeva S, Musayev F, Alhamadsheh MM, Neel Scarsdale J, Tonie Wright H, Reynolds KA. Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates. Bioorg Chem. 2008 Apr;36(2):85-90. Epub 2007 Dec 21. PMID:18096200 doi:10.1016/j.bioorg.2007.11.001
- Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT. Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III. J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8. PMID:11278743 doi:10.1074/jbc.M010762200
- Musayev F, Sachdeva S, Scarsdale JN, Reynolds KA, Wright HT. Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. J Mol Biol. 2005 Mar 11;346(5):1313-21. Epub 2005 Jan 20. PMID:15713483 doi:10.1016/j.jmb.2004.12.044
Categories: Beta-ketoacyl-acyl-carrier-protein synthase I | Mycobacterium tuberculosis | Alhamadsheh, M. | Musayev, F. | Reynolds, K A. | Sachdeva, S. | Scarsdale, J N. | Wright, H T. | Acyltransferase | Cytoplasm | Enzyme inhibitor complex | Fatty acid biosynthesis | Lipid synthesis | Mechanism based inhibitor | Multifunctional enzyme | Myobacterium tuberculosis | Structural basis for substrate specificity | Transferase
