Reserved Sandbox 329
From Proteopedia
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== '''Uridylyl transferases''' == | == '''Uridylyl transferases''' == | ||
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| + | == INTRODUCTION == | ||
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| + | Terminal uridylyl transferases (TUTases) belong to a superfamily of polymerase ß nucleotidyl transferases.<ref>PMID:17785418</ref> TUTases have been isolated from 'Trypanosoma brucei' and also 'Leishmania ssp', parasites causing diseases in humans such as African Sleeping Sickness. | ||
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The bound [[ligand]] is an <scene name='Reserved_Sandbox_329/Ligand/4'>ATP complex</scene> with two Mg<sup>2+</sup> ions. | The bound [[ligand]] is an <scene name='Reserved_Sandbox_329/Ligand/4'>ATP complex</scene> with two Mg<sup>2+</sup> ions. | ||
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== '''References''' == | == '''References''' == | ||
<ref>PMID:17785418</ref> | <ref>PMID:17785418</ref> | ||
Revision as of 01:15, 16 March 2011
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| 2q0d, resolution 2.00Å () | |||||||||
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| Ligands: | , | ||||||||
| Gene: | TUT4 (Trypanosoma brucei) | ||||||||
| Activity: | RNA uridylyltransferase, with EC number 2.7.7.52 | ||||||||
| Related: | 2ikf, 2nom | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Uridylyl transferases
INTRODUCTION
Terminal uridylyl transferases (TUTases) belong to a superfamily of polymerase ß nucleotidyl transferases.[1] TUTases have been isolated from 'Trypanosoma brucei' and also 'Leishmania ssp', parasites causing diseases in humans such as African Sleeping Sickness.
The bound ligand is an with two Mg2+ ions.
