3pna

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Revision as of 05:40, 23 March 2011

Template:STRUCTURE 3pna

Crystal Structure of cAMP bound (91-244)RIa Subunit of cAMP-dependent Protein Kinase

Template:ABSTRACT PUBMED 21081668

About this Structure

3pna is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

• Badireddy S, Yunfeng G, Ritchie M, Akamine P, Wu J, Kim CW, Taylor SS, Qingsong L, Swaminathan K, Anand GS. Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: Conformational selection highlights a new concept in allosteric inhibitor design. Mol Cell Proteomics. 2010 Nov 16. PMID:21081668 doi:10.1074/mcp.M110.004390