1jia
From Proteopedia
(New page: 200px<br /> <applet load="1jia" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jia, resolution 2.13Å" /> '''STRUCTURE OF A BASI...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1JIA is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Gloydius_halys Gloydius halys]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JIA OCA]]. | + | 1JIA is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Gloydius_halys Gloydius halys]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4]]. Structure known Active Sites: ATA and ATB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JIA OCA]]. |
==Reference== | ==Reference== | ||
Structure of a basic phospholipase A2 from Agkistrodon halys Pallas at 2.13 A resolution., Zhao K, Song S, Lin Z, Zhou Y, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):510-21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761847 9761847] | Structure of a basic phospholipase A2 from Agkistrodon halys Pallas at 2.13 A resolution., Zhao K, Song S, Lin Z, Zhou Y, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):510-21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761847 9761847] | ||
[[Category: Gloydius halys]] | [[Category: Gloydius halys]] | ||
| + | [[Category: Phospholipase A(2)]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Lin, Z.]] | [[Category: Lin, Z.]] | ||
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[[Category: phospholipase a2]] | [[Category: phospholipase a2]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:47:34 2007'' |
Revision as of 09:42, 30 October 2007
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STRUCTURE OF A BASIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS AT 2.13A RESOLUTION
Overview
The basic phospholipase A2 isolated from the venom of Agkistrodon halys, Pallas (Agkistrodon blomhoffii Brevicaudus) is a hemolytic toxin and one, of the few PLA2's capable of hydrolyzing the phospholipids of E. coli, membranes in the presence of a bactericidal/permeability-increasing, protein (BPI) of neutrophils. The crystal structure has been determined, and refined at 2.13 A to an R factor of 16.5% (F > 3sigma) with excellent, stereochemistry. A superposition of the two molecules in the asymmetric, unit gives an r. m.s. deviation of 0.326 A for all Calpha atoms. The, refined structure allowed a detailed comparison with other PLA2 species of, known structures. The overall architecture is similar to those of other, PLA2's with a few significant differences. One of which is in the ... [(full description)]
About this Structure
1JIA is a [Single protein] structure of sequence from [Gloydius halys] with CA as [ligand]. Active as [Phospholipase A(2)], with EC number [3.1.1.4]. Structure known Active Sites: ATA and ATB. Full crystallographic information is available from [OCA].
Reference
Structure of a basic phospholipase A2 from Agkistrodon halys Pallas at 2.13 A resolution., Zhao K, Song S, Lin Z, Zhou Y, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):510-21. PMID:9761847
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