3pi5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: '''Unreleased structure''' The entry 3pi5 is ON HOLD until Paper Publication Authors: Rondeau, J.M. Description: Crystal Structure of Human Beta Secretase in Complex with BFG356 ''Pag...)
Line 1: Line 1:
-
'''Unreleased structure'''
+
[[Image:3pi5.jpg|left|200px]]
-
The entry 3pi5 is ON HOLD until Paper Publication
+
<!--
 +
The line below this paragraph, containing "STRUCTURE_3pi5", creates the "Structure Box" on the page.
 +
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 +
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 +
or leave the SCENE parameter empty for the default display.
 +
-->
 +
{{STRUCTURE_3pi5| PDB=3pi5 | SCENE= }}
-
Authors: Rondeau, J.M.
+
===Crystal Structure of Human Beta Secretase in Complex with BFG356===
-
Description: Crystal Structure of Human Beta Secretase in Complex with BFG356
 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:34:31 2010''
+
<!--
 +
The line below this paragraph, {{ABSTRACT_PUBMED_21388807}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 21388807 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_21388807}}
 +
 
 +
==About this Structure==
 +
[[3pi5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PI5 OCA].
 +
 
 +
==Reference==
 +
<ref group="xtra">PMID:21388807</ref><ref group="xtra">PMID:19195886</ref><ref group="xtra">PMID:19195887</ref><references group="xtra"/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Memapsin 2]]
 +
[[Category: Rondeau, J M.]]

Revision as of 07:03, 23 March 2011

Image:3pi5.jpg

Template:STRUCTURE 3pi5

Crystal Structure of Human Beta Secretase in Complex with BFG356

Template:ABSTRACT PUBMED 21388807

About this Structure

3pi5 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rueeger H, Rondeau JM, McCarthy C, Mobitz H, Tintelnot-Blomley M, Neumann U, Desrayaud S. Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1942-7. Epub 2011 Feb 15. PMID:21388807 doi:10.1016/j.bmcl.2011.02.038
  • Machauer R, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Neumann U, Paganetti P. Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1361-5. Epub 2009 Jan 19. PMID:19195886 doi:10.1016/j.bmcl.2009.01.036
  • Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U. Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1366-70. Epub 2009 Jan 22. PMID:19195887 doi:10.1016/j.bmcl.2009.01.055

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3pi5"
Personal tools