3q96
From Proteopedia
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| - | + | [[Image:3q96.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3q96", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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| + | {{STRUCTURE_3q96| PDB=3q96 | SCENE= }} | ||
| - | + | ===B-Raf kinase domain in complex with a tetrahydronaphthalene inhibitor=== | |
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| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_21341678}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21341678 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21341678}} | ||
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| + | ==About this Structure== | ||
| + | [[3q96]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q96 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:21341678</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Aertgeerts, K.]] | ||
| + | [[Category: Sintchak, M D.]] | ||
| + | [[Category: Yano, J.]] | ||
Revision as of 07:04, 23 March 2011
B-Raf kinase domain in complex with a tetrahydronaphthalene inhibitor
Template:ABSTRACT PUBMED 21341678
About this Structure
3q96 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gould AE, Adams R, Adhikari S, Aertgeerts K, Afroze R, Blackburn C, Calderwood EF, Chau R, Chouitar J, Duffey MO, England DB, Farrer C, Forsyth N, Garcia K, Gaulin J, Greenspan PD, Guo R, Harrison SJ, Huang SC, Iartchouk N, Janowick D, Kim MS, Kulkarni B, Langston SP, Liu JX, Ma LT, Menon S, Mizutani H, Paske E, Renou CC, Rezaei M, Rowland RS, Sintchak MD, Smith MD, Stroud SG, Tregay M, Tian Y, Veiby OP, Vos TJ, Vyskocil S, Williams J, Xu T, Yang JJ, Yano J, Zeng H, Zhang DM, Zhang Q, Galvin KM. Design and optimization of potent and orally bioavailable tetrahydronaphthalene raf inhibitors. J Med Chem. 2011 Mar 24;54(6):1836-46. Epub 2011 Feb 22. PMID:21341678 doi:10.1021/jm101479y
