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3ptg
From Proteopedia
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Revision as of 07:26, 23 March 2011
Contents |
Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor
Template:ABSTRACT PUBMED 21316234
About this Structure
3ptg is a 2 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bowers S, Truong AP, Neitz RJ, Neitzel M, Probst GD, Hom RK, Peterson B, Galemmo RA Jr, Konradi AW, Sham HL, Toth G, Pan H, Yao N, Artis DR, Brigham EF, Quinn KP, Sauer JM, Powell K, Ruslim L, Ren Z, Bard F, Yednock TA, Griswold-Prenner I. Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor. Bioorg Med Chem Lett. 2011 Jan 20. PMID:21316234 doi:10.1016/j.bmcl.2011.01.046
Categories: Homo sapiens | Mitogen-activated protein kinase | Artis, D R. | Bard, F. | Bowers, S. | Brigham, E F. | Griswold-Prenner, I. | Hom, R K. | Konradi, A W. | Neitz, J. | Neitzel, M. | Pan, H. | Powell, K. | Probst, G D. | Quinn, K P. | Ruslim, L. | Sauer, J. | Sham, H L. | Toth, G. | Truong, A P. | Yao, N. | Yednock, T A.
