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Cyclin

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(New page: Crystal Structure of Cyclin A3 1vin {{STRUCTURE_1vin| PDB=1vin | SIZE=300| |right|CAPTION=Cyclin A3 1vin }} '''Cyclin''' (CYC) activate CYC...)
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[[Image:1vin.png|left|200px|thumb|Crystal Structure of Cyclin A3 [[1vin]]]]
[[Image:1vin.png|left|200px|thumb|Crystal Structure of Cyclin A3 [[1vin]]]]
{{STRUCTURE_1vin| PDB=1vin | SIZE=300| |right|CAPTION=Cyclin A3 [[1vin]] }}
{{STRUCTURE_1vin| PDB=1vin | SIZE=300| |right|CAPTION=Cyclin A3 [[1vin]] }}
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[[2cci]] - hCYCA2 +CDK2 T160P+CDC homolog<br />
[[2cci]] - hCYCA2 +CDK2 T160P+CDC homolog<br />
[[2wma]], [[2wmb]], [[2x1n]], [[2wev]], [[2wfy]], [[2whb]], [[1okv]], [[1okw]], [[1ol1]], [[1ol2]], [[1urc]], [[1qmz]] - hCYCA2 +CDK2+peptide
[[2wma]], [[2wmb]], [[2x1n]], [[2wev]], [[2wfy]], [[2whb]], [[1okv]], [[1okw]], [[1ol1]], [[1ol2]], [[1urc]], [[1qmz]] - hCYCA2 +CDK2+peptide
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===CYCB1===
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[[2b9r]] – hCYCB1 (mutant)<br />
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[[2jgz]] - hCYCB1 +CDK2
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===CYCD===
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[[2w96]], [[2w99]], [[2w9f]], [[2w9z]] - hCYCD1 +CDK4 (mutant)<br />
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[[3g33]] – hCYCD3 +CDK4
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===CYCE===
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[[1w98]] – hCYCE1 +CDK2 T160P
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===CYCH===
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[[1kxu]], [[1jkw]] – hCYCH
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===CYCK===
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[[2i53]] – hCYCK N-terminal
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===CYCT===
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[[3blh]] - hCYCT1 +CDK9<br />
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[[3blq]] - hCYCT1 +CDK9+ATP<br />
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[[3lq5]] – hCYCT1 (mutant)+CDK9<br />
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[[3blr]] - hCYCT1 +CDK9+inhibitor<br />
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[[3my1]] - hCYCT1 (mutant)+CDK9+inhibitor<br />
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[[3mi9]], [[3mia]] - hCYCT1 +CDK9+protein TAT<br />
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[[2pk2]] - hCYCT1/protein TAT<br />
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[[2w2h]] - CYCT1 +protein TAT + RNA – horse<br />
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[[2ivx]] – hCYCT2 (mutant)
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===CYC===
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[[2pk9]] – yCYC PHO80 +CDK PHO85 – yeast<br />
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[[2pmi]] - yCYC PHO80 +CDK PHO85+ATPgS
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===Viral CYC===
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[[2euf]], [[2f2c]], [[2xo2]], [[1jow]] – V-CYC viral+hCDK6 – Herpesvirus<br />
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[[1bu2]] – V-CYC<br />
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[[1xo2]] - V-CYC + hCDK6 + inhibitor<br />
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[[1g3n]] - V-CYC viral+hCDK6+CDK6 inhibitor<br />
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[[1f5q]] - V-CYC g viral+hCDK2
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 +
 +
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 13:29, 29 March 2011

Image:1vin.png
Crystal Structure of Cyclin A3 1vin

Template:STRUCTURE 1vin

Cyclin (CYC) activate CYC-dependent kinase (CDK) thus acting in the control of the cell cycle. The CYC name derives from the fact that their concentration varies during the cell cycle. Among the CYCs, CYCA are active in the S phase, CYCD regulate the transition from G1 to S.

Contents


3D Structures of Cyclin

CYCA2

3my5, 2wpa, 2wxv, 2wih, 2wip, 3f5x, 3eoc, 3eid, 3ej1, 3dog, 3ddp, 3ddq, 3bht, 2v22, 2uue, 2i40, 2bkz, 2c5n, 2c5o, 2c5v, 2c5x, 2c5y, 2bpm, 2c4g, 1fvv – hCYCA2 +CDK2+inhibitor - human
3bhu, 3bhv, 2uzd, 2uzb, 2uze, 2uzl, 2uzn, 2uzo, 2iw6, 2iw8, 2iw9, 2g9x, 1oi9, 1oiu, 1oiy, 1ogu, 1p5e, 1pkd, 1h1p, 1h1q, 1h1r, 1h1s - hCYCA2 +CDK2 T160P+inhibitor
1fin - hCYCA2 +CDK2
1vyw - hCYCA2 C-terminal + hCDK2
1jst - hCYCA2 +CDK2 T160P
1vin – CYCA3 - bovine
1e9h – hCYCA3 +CDK2 T160P+inhibitor
1h24, 1h25, 1h26, 1h27, 1h28, 1gy3 - hCYCA2 +CDK2 T160P+peptide
2cjm - hCYCA2 +CDK2 T160P Y15P
2cch - hCYCA2 +CDK2 T160P+ATP analog
2cci - hCYCA2 +CDK2 T160P+CDC homolog
2wma, 2wmb, 2x1n, 2wev, 2wfy, 2whb, 1okv, 1okw, 1ol1, 1ol2, 1urc, 1qmz - hCYCA2 +CDK2+peptide

CYCB1

2b9r – hCYCB1 (mutant)
2jgz - hCYCB1 +CDK2

CYCD

2w96, 2w99, 2w9f, 2w9z - hCYCD1 +CDK4 (mutant)
3g33 – hCYCD3 +CDK4

CYCE

1w98 – hCYCE1 +CDK2 T160P

CYCH

1kxu, 1jkw – hCYCH

CYCK

2i53 – hCYCK N-terminal

CYCT

3blh - hCYCT1 +CDK9
3blq - hCYCT1 +CDK9+ATP
3lq5 – hCYCT1 (mutant)+CDK9
3blr - hCYCT1 +CDK9+inhibitor
3my1 - hCYCT1 (mutant)+CDK9+inhibitor
3mi9, 3mia - hCYCT1 +CDK9+protein TAT
2pk2 - hCYCT1/protein TAT
2w2h - CYCT1 +protein TAT + RNA – horse
2ivx – hCYCT2 (mutant)

CYC

2pk9 – yCYC PHO80 +CDK PHO85 – yeast
2pmi - yCYC PHO80 +CDK PHO85+ATPgS

Viral CYC

2euf, 2f2c, 2xo2, 1jow – V-CYC viral+hCDK6 – Herpesvirus
1bu2 – V-CYC
1xo2 - V-CYC + hCDK6 + inhibitor
1g3n - V-CYC viral+hCDK6+CDK6 inhibitor
1f5q - V-CYC g viral+hCDK2

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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