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2xyn

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[[Image:2xyn.png|left|200px]]
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===HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680===
===HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680===
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{{ABSTRACT_PUBMED_21417343}}
==About this Structure==
==About this Structure==
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2XYN is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3nsv 3nsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYN OCA].
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[[2xyn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3nsv 3nsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYN OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20077570</ref><references group="xtra"/>
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<ref group="xtra">PMID:21417343</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: Yue, W W.]]
[[Category: Yue, W W.]]
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[[Category: Cell adhesion]]
 
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[[Category: Sgc]]
 
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[[Category: Structural genomics consortium]]
 
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[[Category: Transferase]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:23:57 2010''
 

Revision as of 07:32, 30 March 2011

Image:2xyn.png

Template:STRUCTURE 2xyn

HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680

Template:ABSTRACT PUBMED 21417343

About this Structure

2xyn is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3nsv. Full crystallographic information is available from OCA.

Reference

  • Salah E, Ugochukwu E, Barr AJ, von Delft F, Knapp S, Elkins JM. Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class. J Med Chem. 2011 Mar 18. PMID:21417343 doi:10.1021/jm101506n

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