2xyn

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Revision as of 07:32, 30 March 2011

Template:STRUCTURE 2xyn

HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680

Template:ABSTRACT PUBMED 21417343

About this Structure

2xyn is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3nsv. Full crystallographic information is available from OCA.

Reference

  • Salah E, Ugochukwu E, Barr AJ, von Delft F, Knapp S, Elkins JM. Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class. J Med Chem. 2011 Mar 18. PMID:21417343 doi:10.1021/jm101506n

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