3o0u

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'''Unreleased structure'''
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[[Image:3o0u.jpg|left|200px]]
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The entry 3o0u is ON HOLD until Paper Publication
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{{STRUCTURE_3o0u| PDB=3o0u | SCENE= }}
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Authors: Fradera, X., van Zeeland, M., Uitdehaag, J.C.M.
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===Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG===
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Description: Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 4 08:51:15 2010''
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{{ABSTRACT_PUBMED_20843687}}
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==About this Structure==
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[[3o0u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O0U OCA].
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==Reference==
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<ref group="xtra">PMID:20843687</ref><references group="xtra"/>
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[[Category: Cathepsin K]]
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[[Category: Homo sapiens]]
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[[Category: Fradera, X.]]
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[[Category: Uitdehaag, J C.M.]]
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[[Category: Zeeland, M van.]]

Revision as of 08:04, 30 March 2011

Image:3o0u.jpg

Template:STRUCTURE 3o0u

Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG

Template:ABSTRACT PUBMED 20843687

About this Structure

3o0u is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rankovic Z, Cai J, Kerr J, Fradera X, Robinson J, Mistry A, Finlay W, McGarry G, Andrews F, Caulfield W, Cumming I, Dempster M, Waller J, Arbuckle W, Anderson M, Martin I, Mitchell A, Long C, Baugh M, Westwood P, Kinghorn E, Jones P, Uitdehaag JC, van Zeeland M, Potin D, Saniere L, Fouquet A, Chevallier F, Deronzier H, Dorleans C, Nicolai E. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG. Bioorg Med Chem Lett. 2010 Aug 24. PMID:20843687 doi:10.1016/j.bmcl.2010.08.101

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