2xnn
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2xnn is ON HOLD Authors: Mas-Droux, C., Bayliss, R. Description: Structure of Nek2 bound to CCT242430 ''Page seeded by [http://oca.weizmann.ac.il/...) |
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| - | + | [[Image:2xnn.jpg|left|200px]] | |
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| + | {{STRUCTURE_2xnn| PDB=2xnn | SCENE= }} | ||
| - | + | ===STRUCTURE OF NEK2 BOUND TO CCT242430=== | |
| - | Description: Structure of Nek2 bound to CCT242430 | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_21366329}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21366329 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21366329}} | ||
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| + | ==About this Structure== | ||
| + | [[2xnn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNN OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:21366329</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Bayliss, R.]] | ||
| + | [[Category: Mas-Droux, C.]] | ||
Revision as of 08:09, 30 March 2011
STRUCTURE OF NEK2 BOUND TO CCT242430
Template:ABSTRACT PUBMED 21366329
About this Structure
2xnn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Solanki S, Innocenti P, Mas-Droux C, Boxall K, Barillari C, van Montfort RL, Aherne GW, Bayliss R, Hoelder S. Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J Med Chem. 2011 Mar 24;54(6):1626-39. Epub 2011 Mar 2. PMID:21366329 doi:10.1021/jm1011726
