Prp19

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==Introduction==
==Introduction==
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PRP19 is a splicing factor which is essential for proper pre-mRNA processing.<ref>PMID:10092627</ref>Its presence is required prior to the first splicing step
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PRP19 is a splicing factor which is essential for proper pre-mRNA processing.<ref>PMID:10092627</ref>Its presence is required prior to the first splicing step <ref>PMID:8248176</ref>

Revision as of 02:28, 31 March 2011

PDB ID 3lrv

Drag the structure with the mouse to rotate
3lrv, resolution 2.60Å ()
Ligands:
Gene: PRP19, PSO4, YLL036C (Saccharomyces cerevisiae)


Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Introduction

PRP19 is a splicing factor which is essential for proper pre-mRNA processing.[1]Its presence is required prior to the first splicing step [2]


References

  1. Tsai WY, Chow YT, Chen HR, Huang KT, Hong RI, Jan SP, Kuo NY, Tsao TY, Chen CH, Cheng SC. Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing. J Biol Chem. 1999 Apr 2;274(14):9455-62. PMID:10092627
  2. Tarn WY, Lee KR, Cheng SC. Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10821-5. PMID:8248176 doi:10.1073/pnas.90.22.10821

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