Ribonuclease

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(New page: Crystal Structure of Ribonuclease 1jvt {{STRUCTURE_1jvt| PDB=1jvt | SIZE=300| |right|CAPTION=Ribonuclease 1jvt }} '''Ribonuclease''' (RNase...)
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[[Image:1jvt.png|left|200px|thumb|Crystal Structure of Ribonuclease [[1jvt]]]]
[[Image:1jvt.png|left|200px|thumb|Crystal Structure of Ribonuclease [[1jvt]]]]
{{STRUCTURE_1jvt| PDB=1jvt | SIZE=300| |right|CAPTION=Ribonuclease [[1jvt]] }}
{{STRUCTURE_1jvt| PDB=1jvt | SIZE=300| |right|CAPTION=Ribonuclease [[1jvt]] }}
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== 3D Structures of Ribonuclease ==
== 3D Structures of Ribonuclease ==
 +
 +
===RNase I===
 +
 +
3mwq]], [[3mwq]], [[3mx8]], [[3i67]], [[3i6f]], [[3i6h]], [[3i6j]], [[3i7w]], [[3eux]], [[3euy]], [[3euz]], [[3ev0]], [[3ev1]], [[3ev2]], [[3ev3]], [[3ev4]], [[3ev5]], [[3ev6]], [[3dh5]], [[2e3w]], [[2g4w]], [[2g4x]], [[2gbq]], [[2blp]], [[2blz]], [[1jvt]], [[1jvv]], [[1js0]], [[1fs3]], [[1kf2]], [[1kf3]], [[1kf4]], [[1kf5]], [[1kf7]], [[1kf8]], [[1aqp]], [[1a2w]], [[1rnw]], [[1rnz]], [[1rno]], [[1rnq]], [[1rbx]], [[1ssc]], [[3srn]], [[4srn]], [[1srn]], [[5rsa]] - bRNase I pancreatic]] - bovine

 +
3a1r]] - bRNase I pancreatic]] - neutron

 +
3i7x]], [[3i7y]], [[3fkz]], [[3fl3]], [[3dh6]], [[3di7]], [[3di8]], [[3di9]], [[3dib]], [[3dic]], [[2oqf]], [[3bcm]], [[3bco]], [[3bcp]], [[2nui]], [[2op2]], [[1ymn]], [[1ymr]], [[1ymw]], [[2apq]], [[1izp]], [[1izq]], [[1izr]], [[1kh8]], [[1c8w]], [[1eic]], [[1eid]], [[1eie]], [[1dy5]], [[3rsd]], [[3rsk]], [[1ssa]], [[1ssb]] - bRNase I pancreatic (mutant)

 +
3lxo]], [[3jw1]], [[3djo]], [[3djp]], [[3djq]], [[3djv]], [[3djx]], [[3dxg]], [[3dxh]], [[2w5g]], [[2w5i]], [[2w5k]], [[2w5l]], [[2w5m]], [[3d6o]], [[3d6p]], [[3d6q]], [[3d7b]], [[3d8y]], [[3d8z]], [[2qca]], [[2g8r]], [[1z6d]], [[1z6s]], [[1u1b]], [[1w4o]], [[1w4p]], [[1w4q]], [[1wbu]], [[1o0f]], [[1jn4]], [[1jvu]], [[1f0v]], [[1ruv]], [[1rnm]], [[1rnn]], [[1rbw]], [[1rca]], [[1rpf]], [[1rpg]], [[1rph]], [[1rbw]], [[1rca]], [[1rpf]], [[1rpg]], [[1rph]], [[1rnc]], [[1rnd]], [[1rob]], [[1rta]], [[1rtb]] - bRNase I pancreatic + nucleotide<br />
 +

6rsa]] - bRNase I pancreatic + nucleotide<br />]] - neutron

 +
3fl0 ]], [[3fl1]], [[4rsk]] - bRNase I pancreatic (mutant) + nucleotide<br />

 +
2xog]], [[2xoi]], [[2q4g]], [[1dfj]] - bRNase I pancreatic + inhibitor

 +
1rar]], [[1ras]] - bRNase I pancreatic fluorescent

 +
2p42]], [[2p43]], [[2p44]], [[2p45 ]], [[2p46]], [[2p47]], [[2p48]], [[2p49]], [[2p4a]], [[1bzq]] - bRNase I + antibody
 +

3f8g]], [[2e0j]], [[2e0l]], [[2e0m]], [[2e0o]], [[1h8x]], [[1e21]], [[1dza]] - hRNase I pancreatic (mutant)]] - human

 +
2k11]] - hRNase I pancreatic]] - NMR<BR />

 +
1z7x]] - hRNase I + inhibitor

 +
3ljd]], [[3ln8]], [[2vq8]], [[2vq9]] - ZeRNase I – Zebrafish
 +

2pqx]], [[2pqy]] - EcRNase I

 +
2z70]], [[2ea1]] - EcRNAse I + DNA<BR />

 +
 +
===

 RNase II===
 +
 +
2ix0]], [[2id0]] - EcRNase II

 +
2ix1]] - EcRNase II (mutant)

 +
1m58]], [[1km8]], [[1km9- BuRNase 2]] - Bullfrog

 +
1bc4]] - BuRNase 2 ]] - NMR<BR />

 +
1m07]] - BuRNase 2 + DNA<BR />


 +
 +
===RNase III===
 +
 +
2nue]], [[2nuf]], [[2nug]], [[1yyk]], [[1yyw]] - AaRNase III + RNA]] - Aquifex aeolicus

 +
2ez6]], [[1yyo]], [[1yz9]], [[1rc7]] - AaRNase III (mutant) + RNA 

 +
1rc5]], [[1i4s]], [[1jfz]] - AaRNase III N-terminal

 +
1z5f]] - BuRNase III 

 +
2a11]] - MtRNase III]] - Mycobacterium tuberculosis

 +
1o0w]] - TmRNase III]] - Thermotoga maritima


 +
2kb5]] - hRNase 3]] - NMR<BR />

 +
1dyt]], [[1qmt]] - hRNase 3

 +
1h1h]] - hRNase 3 + nucleotide<br />


 +
 +
===RNase 4===
 +
 +
1wdy]] - hRNase 4

 +
2rnf]], [[1rnf]] - hRNase 4 + nucleotide<br />

 +
1kvz]] - BuRNase 4]] - NMR<BR />


 +
 +
===RNase 5===
 +
 +
1un3]], [[1un4]], [[1un5]], [[1gv7]] - hRNase 5 (mutant)

 +
1h0d]] - hRNase 5 + antibody
 +

3lje]] - ZeRNase 5
 +
 +
===RNase 7===
 +
 +


2hky]] - hRNase 7]] - NMR<BR />


 +
 +
===RNase A===
 +
 +
1rra]] - RNase A (mutant) – rat
 +
 +
===RNase BA===
 +
 +
1x1u]], [[1x1x]], [[1x1y]], [[1b27]], [[1b2u]], [[1b3s]] - BaRNase BA + Barstar (mutant)]] - Bacillus amyloliquefaciens

 +
3da7]], [[1brs]], [[1bgs]] - BaRNase BA + Barstar 

 +
1b2s]], [[2za4]] - BaRNase BA (mutant) + Barstar (mutant)
 +
1brn]], [[2kf5]], [[2kf6]], [[1rnb]] - BaRNase BA + nucleotide<br />
 +

3kch]], [[2f4y]], [[2f56]], [[2f5m]], [[2f5w]] - BaRNase BA crosslinked

 +
2kf3]], [[2kf4]], [[1fw7]], [[1bnr]] - BaRNase BA – NMR<BR />
 +

1yvs]], [[1b2x]], [[1a2p]], [[1bni]], [[1bnj]] - BaRNase BA 

 +
1b20]], [[1b21]], [[1b2z]], [[1bne]], [[1bnf]], [[1bng]], [[1brh]], [[1bri]], [[1brj]], [[1brk]], [[1bns]], [[1brg]], [[1bsa]], [[1bsb]], [[1bsc]], [[1bsd]], [[1bse]], [[1ban]], [[1bao]] - BaRNase BA (mutant)


 +
 +
===RNase D===
 +
 +
1yt3]] - EcRNase D

 -Eschericia coli
 +
 +
===RNase E===
 +
 +
2vmk]], [[2c4r]], [[2bx2]] - EcRNase E catalytic domain
 +

1slj]] - EcRNase E S1 domain]] - NMR<BR />

 +
1smx]], [[1sn8]] - EcRNase E S1 domain 

 +
2vrt]], [[2c0b]] - EcRNase E catalytic domain + RNA
 +
 +
===RNase H===
 +
 +
3h7i]], [[3h8s]], [[3h8w]] - T4RNase H (mutant)]] - Enterobacteria phage T4

 +
2ihn]] - T4RNase H (mutant) + DNA<BR />

 +
3h8j]], [[1tfr- T4RNase H 

 +
2rpi]], [[1ril]] - TtRNase H]] - Thermus thermophilus]] - NMR<BR />

 +
1jl2]] - EcRNase H /TtRNase H 

 +
3d0p]] - BhRNase H (mutant) + DNA<BR />]] - Bacillus halodurans

 +
1zbf]] - BhRNase H (mutant) 

 +
2r7y]], [[2g8f]], [[2g8h]], [[2g8i]], [[2g8k]], [[2g8u]], [[2g8v]], [[2g8w]], [[1zbi]], [[1zbl]] - BhRNase H (mutant) + RNA + DNA<BR />


 +
 +
===RNase HI===
 +
 +
2qk9]], [[2qkb]], [[2qkk]] - hRNase HI (mutant) + RNA + DNA<BR />

 +
3h08]] - RNase HI]] - Chlorobaculum tepidum

 +
3aa2]], [[3aa3]], [[3aa4]], [[3aa5]], [[2yv0]], [[2z1g]], [[2z1h]], [[2z1i]], [[2z1j]], [[1wse]], [[1wsf]], [[1wsg]], [[1wsh]], [[1wsi]], [[1wsj]], [[1jxb]], [[1jl1]], [[1f21]], [[1kva]], [[1kvb]], [[1kvc]], [[1goa]], [[1gob]], [[1goc]] - EcRNase HI (mutant)]] - Escherichia coli

 +
1g15]], [[1rdd]] - EcRNase HI

 +
1rch]] - EcRNase HI]] - NMR<BR />

 +
2zqb]] - SoRNase HI (mutant)]] - Shewanella oneidensis
 +

2e4l]] - SoRNase HI 

 +
3bsu]] - hRNase HI catalytic domain + RNA + DNA<BR />

 +
2ehg]] - RNase HI]] - Sulfolobus tokodaii

 +
1qhk]] - RNase HI N-terminal]] - yeast – NMR<BR />
 +
 +
===RNase HII===
 +
 +


3p83]] - AfRNase HII + DNA<BR /> polymerase sliding clamp]] - Archaeoglobus fulgidus

 +
1i39]], [[1i3a]] - AfRNAse HII

 +
3puf]], [[3p56]], [[3p5j]] - hRNAse H2 subunits a+b+g 

 +
3kio]] - mRNase H2 subunits a+b+g 
- mouse

 +
3o3g]] - TmRNase HII + DNA<BR /> 

 +
3o3f]], [[3o3h]] - TmRNase HII (mutant) + DNA<BR />
 +

2etj]] - TmRNase HII 

 +
1x1p]] - TkRNase HII

 +
2dfe]], [[2dff]], [[2dfh]] - TkRNase HII (mutant)]] - Thermococcus kodakarensis

 +
1eke]] - RNase HII]] - Methanocalcococcus jannaschii


 +
2d0a]], [[2d0b]], [[2d0c]] - RNase HIII]] - Geobacillus stearothermophilus


 +
 +
===RNase J===
 +
 +
3bk1]] - TtRNase J

 +
3bk2]] - TtRNase J + nucleotide<br />


 +
 +
===RNase LE===
 +
 +
1dix]] - RNase LE]] - Solanum lycopersicum


 +
 +
===RNase MS===
 +
 +
1rms]] - RNase MS + nucleotide<br />]] - Aspergillus phoenicis
 +
 +
===RNase MC1===
 +
 +
1v9h]], [[1j1f]], [[1j1g]] - McRNase MC1 (mutant) + nucleotide<br />]] - Momordica charantia

 +
1ucd]] - McRNase MC1 + nucleotide<br /> 

 +
1bk7]] - McRNase MC1


 +
 +
===RNase NT===
 +
 +
1vcz]], [[1vd1]], [[1vd3]] - RNase NT + nucleotide<br />]] - Nicotiana glutinosa


 +
 +
===RNase P===
 +
 +
3ok7]], [[3okb]] - TmRNase P + TmRNase P RNA + tRNA Phe

 +
1nz0]] - TmRNase P

 +
1d6t]] - RNase P]] - Staphylococcus aureus
 +

2a64]] - RNase P (mutant)]] - Bacillus stearothermophilus


 +
 +
===RNase PH===
 +
 +
3dd6]] - RNase PH]] - Bacillus anthracis

 +
1oyp]], [[1oyr]], [[1oys]] - RNase PH]] - Bacillus subtilis

 +
1r6l]], [[1r6m]] - PaRNase PH]] - Pseudomonas aeruginosa

 +
3b4t]] - MtRNase PH]] - Mycobacterium tuberculosis

 +
1udn]] - AaRNase PH

 +
1udo]], [[1udq]], [[1uds]] - AaRNase PH (mutant)


 +
 +
===RNase S===
 +
 +
3oqy]], [[3oqz]], [[3or0]], [[1z3l]], [[1z3m]], [[1z3p]], [[1y92]], [[1y94]], [[1fev]], [[1d5d]], [[1d5e]], [[1d5h]], [[2rln]] - bRNase S seminal (mutant)

 +
1tq9]], [[1r5c]] - bRNase S + nucleotide<br />

 +
1r5d]], [[1r3m]], [[1n1x]], [[1n3z]], [[1j7z]], [[1j80]], [[1j81]], [[1j82]], [[1cjq]], [[1cjr]], [[1bsr]] - bRNase S

 +
 +
===RNase S3===
 +
 +
1iqq]] - RNase S3]] - Japanese pear
 +
 +
===RNase SA===
 +
 +
3a5e]], [[1zgx]], [[1ynv]], [[1t2h]], [[1t2i]], [[1uci]], [[1ucj]], [[1uck]], [[1ucl]], [[1i70]], [[1i8v]], [[1box]] - SaRNase SA guanyl-specific (mutant)]] - Streptomyces aureofaciens

 +
1lni]] - SaRNase SA 

 +
1gmp]], [[1gmq]], [[1gmr]] - SaRNase SA +nucleotide<br />

 +
1ay7]] - SaRNase SA + Barstar
 +
1rsn]] - SaRNase SA + cyclophosphothiolate
 +
 +
===RNase SA2===
 +
 +
3dgy]], [[3dh2]], [[3d4a]], [[3d5g]], [[3d5i]] - SaRNase SA2 + mononucleotide<br />
 +
 +
===RNase SA3===
 +
 +
1mgr]], [[1mgw]] - SaRNase SA3
 +
 +
===RNase SF11===
 +
 +


1ioo]] - RNase SF11]] - Nicotiana alata


 +
 +
===RNase T===
 +
 +
2is3]] - EcRNase T

 +
2f96]] - PaRNase T 


 +
 +
===RNase T1===
 +
 +
1tto]] - AoRNase T1]] - Aspergillus oryzae

 +
1q9e]], [[1iyy]], [[1i2e]], [[1i2f]], [[1i2g]], [[1i3f]], [[1i3i]], [[1hz1]], [[1fys]], [[1fzu]], [[1ch0]], [[4bir]], [[3bir 5bir]] - AoRNase T1 (mutant)
 +

1lov]], [[1low]], [[1loy]], [[1i0v]], [[1i0x]], [[1b2m]], [[1rhl]], [[1bir]], [[1rgk]], [[1rgl]] - AoRNase T1 (mutant) + nucleotide<br />
 +
1bvi]], [[2bu4]], [[2hoh]], [[4hoh]], [[5hoh]], [[3hoh]], [[2gsp]], [[3gsp]], [[4gsp]], [[5gsp]], [[6gsp]], [[7gsp]], [[1gsp]], [[1det]], [[1rls]], [[1lra]], [[1rga]] - AoRNase T1 + nucleotide<br />

 +
1ygw]] - AoRNase T1 – NMR<BR />
 +
 +
===RNase U2===
 +
 +
3agn]], [[3ago]], [[3ahw]] - UsRNase U2 + AMP]] - Ustilago sphaerogena

 +
1rtu]] - UsRNase U2
 +
 +
===RNase U2B===
 +
 +
3ahs]] - UsRNase U2B
 +
 +
===RNase Z ===
 +
 +
2e7y]] - TmRNase Z
 +
2fk6]] - BsRNase Z (mutant) + tRNA Thr 

 +
1y44]] - BsRNase Z (mutant)
 +
 +
===Oligoribonuclease===
 +
 +
2igi]], [[1yta – EcORNase
 +

2gbz]] - ORNase]] - Xanthomonas campestris
 +

1j9a]] - ORNase]] - Haemophilus influenzae
 +
 +
===Polynucleotide Phosphorylase===
 +
 +
3cdi]] - EcPNPase
 +
3gll]] - EcPNPase core
 +
3cdj]] - EcPNPase C-terminal truncated
 +
1e3h]], [[1e3p]] - PNPase]] - Streptomyces antibioticus
 +
3gcm]], [[3gme]], [[3h1c]] - EcPNPase + RNase E recognition domain
 +
3h36]] - PNPase fragment]] - Streptococcus mutans

Revision as of 07:49, 31 March 2011

Image:1jvt.png
Crystal Structure of Ribonuclease 1jvt

Template:STRUCTURE 1jvt

Ribonuclease (RNase) degrades RNA. The endonucleases cleave single or double stranded RNA and include RNase III, A, T1 H and P. Exo-RNases remove terminal nucleotide
from the ends of the RNA molecule. They include RNase II D, T, PH, Polynucleotide Phosphorylase (PNPase) and oligoribonuclease (ORNase).
 RNase A cleaves C or U of single-stranded RNA (ssRNA). RNase BA is RNase from Bacillus amyloliquefaciens. RNase D degrades 3'-end pre-tRNA. RNase H cleaves RNA/DNA double-strand to produce ssDNA. RNase I cleaves 3'-end of ssRNA. RNase II degrades 3'-end ssRNA. RNase III cleaves rRNA. RNase P is a ribozyme. RNase S is RNase A cleaved by subtilisin. RNase SA is RNase from Streptomyces auerofaciens. RNase T is involved in RNA maturation. RNase T1 cleaves 3'-end G from ssRNA. RNase U2 cleaves 3'-end A from ssRNA.

3D Structures of Ribonuclease

RNase I

3mwq]], 3mwq, 3mx8, 3i67, 3i6f, 3i6h, 3i6j, 3i7w, 3eux, 3euy, 3euz, 3ev0, 3ev1, 3ev2, 3ev3, 3ev4, 3ev5, 3ev6, 3dh5, 2e3w, 2g4w, 2g4x, 2gbq, 2blp, 2blz, 1jvt, 1jvv, 1js0, 1fs3, 1kf2, 1kf3, 1kf4, 1kf5, 1kf7, 1kf8, 1aqp, 1a2w, 1rnw, 1rnz, 1rno, 1rnq, 1rbx, 1ssc, 3srn, 4srn, 1srn, 5rsa - bRNase I pancreatic]] - bovine
 3a1r]] - bRNase I pancreatic]] - neutron
 3i7x]], 3i7y, 3fkz, 3fl3, 3dh6, 3di7, 3di8, 3di9, 3dib, 3dic, 2oqf, 3bcm, 3bco, 3bcp, 2nui, 2op2, 1ymn, 1ymr, 1ymw, 2apq, 1izp, 1izq, 1izr, 1kh8, 1c8w, 1eic, 1eid, 1eie, 1dy5, 3rsd, 3rsk, 1ssa, 1ssb - bRNase I pancreatic (mutant)
 3lxo]], 3jw1, 3djo, 3djp, 3djq, 3djv, 3djx, 3dxg, 3dxh, 2w5g, 2w5i, 2w5k, 2w5l, 2w5m, 3d6o, 3d6p, 3d6q, 3d7b, 3d8y, 3d8z, 2qca, 2g8r, 1z6d, 1z6s, 1u1b, 1w4o, 1w4p, 1w4q, 1wbu, 1o0f, 1jn4, 1jvu, 1f0v, 1ruv, 1rnm, 1rnn, 1rbw, 1rca, 1rpf, 1rpg, 1rph, 1rbw, 1rca, 1rpf, 1rpg, 1rph, 1rnc, 1rnd, 1rob, 1rta, 1rtb - bRNase I pancreatic + nucleotide

6rsa]] - bRNase I pancreatic + nucleotide
]] - neutron
 3fl0 ]], 3fl1, 4rsk - bRNase I pancreatic (mutant) + nucleotide

 2xog]], 2xoi, 2q4g, 1dfj - bRNase I pancreatic + inhibitor
 1rar]], 1ras - bRNase I pancreatic fluorescent
 2p42]], 2p43, 2p44, 2p45 , 2p46, 2p47, 2p48, 2p49, 2p4a, 1bzq - bRNase I + antibody 
3f8g]], 2e0j, 2e0l, 2e0m, 2e0o, 1h8x, 1e21, 1dza - hRNase I pancreatic (mutant)]] - human
 2k11]] - hRNase I pancreatic]] - NMR

 1z7x]] - hRNase I + inhibitor
 3ljd]], 3ln8, 2vq8, 2vq9 - ZeRNase I – Zebrafish 
2pqx]], 2pqy - EcRNase I
 2z70]], 2ea1 - EcRNAse I + DNA



 RNase II

2ix0]], 2id0 - EcRNase II
 2ix1]] - EcRNase II (mutant)
 1m58]], 1km8, 1km9- BuRNase 2 - Bullfrog
 1bc4]] - BuRNase 2 ]] - NMR

 1m07]] - BuRNase 2 + DNA




RNase III

2nue]], 2nuf, 2nug, 1yyk, 1yyw - AaRNase III + RNA]] - Aquifex aeolicus
 2ez6]], 1yyo, 1yz9, 1rc7 - AaRNase III (mutant) + RNA 
 1rc5]], 1i4s, 1jfz - AaRNase III N-terminal
 1z5f]] - BuRNase III 
 2a11]] - MtRNase III]] - Mycobacterium tuberculosis
 1o0w]] - TmRNase III]] - Thermotoga maritima

 2kb5]] - hRNase 3]] - NMR

 1dyt]], 1qmt - hRNase 3
 1h1h]] - hRNase 3 + nucleotide




RNase 4

1wdy]] - hRNase 4
 2rnf]], 1rnf - hRNase 4 + nucleotide

 1kvz]] - BuRNase 4]] - NMR




RNase 5

1un3]], 1un4, 1un5, 1gv7 - hRNase 5 (mutant)
 1h0d]] - hRNase 5 + antibody 
3lje]] - ZeRNase 5

RNase 7



2hky]] - hRNase 7]] - NMR




RNase A

1rra]] - RNase A (mutant) – rat

RNase BA

1x1u]], 1x1x, 1x1y, 1b27, 1b2u, 1b3s - BaRNase BA + Barstar (mutant)]] - Bacillus amyloliquefaciens
 3da7]], 1brs, 1bgs - BaRNase BA + Barstar 
 1b2s]], 2za4 - BaRNase BA (mutant) + Barstar (mutant) 1brn]], 2kf5, 2kf6, 1rnb - BaRNase BA + nucleotide

3kch]], 2f4y, 2f56, 2f5m, 2f5w - BaRNase BA crosslinked
 2kf3]], 2kf4, 1fw7, 1bnr - BaRNase BA – NMR

1yvs]], 1b2x, 1a2p, 1bni, 1bnj - BaRNase BA 
 1b20]], 1b21, 1b2z, 1bne, 1bnf, 1bng, 1brh, 1bri, 1brj, 1brk, 1bns, 1brg, 1bsa, 1bsb, 1bsc, 1bsd, 1bse, 1ban, 1bao - BaRNase BA (mutant)



RNase D

1yt3]] - EcRNase D

 -Eschericia coli

RNase E

2vmk]], 2c4r, 2bx2 - EcRNase E catalytic domain 
1slj]] - EcRNase E S1 domain]] - NMR

 1smx]], 1sn8 - EcRNase E S1 domain 
 2vrt]], 2c0b - EcRNase E catalytic domain + RNA

RNase H

3h7i]], 3h8s, 3h8w - T4RNase H (mutant)]] - Enterobacteria phage T4
 2ihn]] - T4RNase H (mutant) + DNA

 3h8j]], [[1tfr- T4RNase H 
 2rpi]], 1ril - TtRNase H]] - Thermus thermophilus]] - NMR

 1jl2]] - EcRNase H /TtRNase H 
 3d0p]] - BhRNase H (mutant) + DNA
]] - Bacillus halodurans
 1zbf]] - BhRNase H (mutant) 
 2r7y]], 2g8f, 2g8h, 2g8i, 2g8k, 2g8u, 2g8v, 2g8w, 1zbi, 1zbl - BhRNase H (mutant) + RNA + DNA




RNase HI

2qk9]], 2qkb, 2qkk - hRNase HI (mutant) + RNA + DNA

 3h08]] - RNase HI]] - Chlorobaculum tepidum
 3aa2]], 3aa3, 3aa4, 3aa5, 2yv0, 2z1g, 2z1h, 2z1i, 2z1j, 1wse, 1wsf, 1wsg, 1wsh, 1wsi, 1wsj, 1jxb, 1jl1, 1f21, 1kva, 1kvb, 1kvc, 1goa, 1gob, 1goc - EcRNase HI (mutant)]] - Escherichia coli
 1g15]], 1rdd - EcRNase HI
 1rch]] - EcRNase HI]] - NMR

 2zqb]] - SoRNase HI (mutant)]] - Shewanella oneidensis 
2e4l]] - SoRNase HI 
 3bsu]] - hRNase HI catalytic domain + RNA + DNA

 2ehg]] - RNase HI]] - Sulfolobus tokodaii
 1qhk]] - RNase HI N-terminal]] - yeast – NMR

RNase HII



3p83]] - AfRNase HII + DNA
polymerase sliding clamp]] - Archaeoglobus fulgidus
 1i39]], 1i3a - AfRNAse HII
 3puf]], 3p56, 3p5j - hRNAse H2 subunits a+b+g 
 3kio]] - mRNase H2 subunits a+b+g 
- mouse
 3o3g]] - TmRNase HII + DNA

 3o3f]], 3o3h - TmRNase HII (mutant) + DNA

2etj]] - TmRNase HII 
 1x1p]] - TkRNase HII
 2dfe]], 2dff, 2dfh - TkRNase HII (mutant)]] - Thermococcus kodakarensis
 1eke]] - RNase HII]] - Methanocalcococcus jannaschii

 2d0a]], 2d0b, 2d0c - RNase HIII]] - Geobacillus stearothermophilus



RNase J

3bk1]] - TtRNase J
 3bk2]] - TtRNase J + nucleotide




RNase LE

1dix]] - RNase LE]] - Solanum lycopersicum



RNase MS

1rms]] - RNase MS + nucleotide
]] - Aspergillus phoenicis

RNase MC1

1v9h]], 1j1f, 1j1g - McRNase MC1 (mutant) + nucleotide
]] - Momordica charantia
 1ucd]] - McRNase MC1 + nucleotide

 1bk7]] - McRNase MC1



RNase NT

1vcz]], 1vd1, 1vd3 - RNase NT + nucleotide
]] - Nicotiana glutinosa



RNase P

3ok7]], 3okb - TmRNase P + TmRNase P RNA + tRNA Phe
 1nz0]] - TmRNase P
 1d6t]] - RNase P]] - Staphylococcus aureus 
2a64]] - RNase P (mutant)]] - Bacillus stearothermophilus



RNase PH

3dd6]] - RNase PH]] - Bacillus anthracis
 1oyp]], 1oyr, 1oys - RNase PH]] - Bacillus subtilis
 1r6l]], 1r6m - PaRNase PH]] - Pseudomonas aeruginosa
 3b4t]] - MtRNase PH]] - Mycobacterium tuberculosis
 1udn]] - AaRNase PH
 1udo]], 1udq, 1uds - AaRNase PH (mutant)



RNase S

3oqy]], 3oqz, 3or0, 1z3l, 1z3m, 1z3p, 1y92, 1y94, 1fev, 1d5d, 1d5e, 1d5h, 2rln - bRNase S seminal (mutant)
 1tq9]], 1r5c - bRNase S + nucleotide

 1r5d]], 1r3m, 1n1x, 1n3z, 1j7z, 1j80, 1j81, 1j82, 1cjq, 1cjr, 1bsr - bRNase S


RNase S3

1iqq]] - RNase S3]] - Japanese pear

RNase SA

3a5e]], 1zgx, 1ynv, 1t2h, 1t2i, 1uci, 1ucj, 1uck, 1ucl, 1i70, 1i8v, 1box - SaRNase SA guanyl-specific (mutant)]] - Streptomyces aureofaciens
 1lni]] - SaRNase SA 
 1gmp]], 1gmq, 1gmr - SaRNase SA +nucleotide

 1ay7]] - SaRNase SA + Barstar 1rsn]] - SaRNase SA + cyclophosphothiolate

RNase SA2

3dgy]], 3dh2, 3d4a, 3d5g, 3d5i - SaRNase SA2 + mononucleotide

RNase SA3

1mgr]], 1mgw - SaRNase SA3

RNase SF11



1ioo]] - RNase SF11]] - Nicotiana alata



RNase T

2is3]] - EcRNase T
 2f96]] - PaRNase T 



RNase T1

1tto]] - AoRNase T1]] - Aspergillus oryzae
 1q9e]], 1iyy, 1i2e, 1i2f, 1i2g, 1i3f, 1i3i, 1hz1, 1fys, 1fzu, 1ch0, 4bir, 3bir 5bir - AoRNase T1 (mutant) 
1lov]], 1low, 1loy, 1i0v, 1i0x, 1b2m, 1rhl, 1bir, 1rgk, 1rgl - AoRNase T1 (mutant) + nucleotide
1bvi]], 2bu4, 2hoh, 4hoh, 5hoh, 3hoh, 2gsp, 3gsp, 4gsp, 5gsp, 6gsp, 7gsp, 1gsp, 1det, 1rls, 1lra, 1rga - AoRNase T1 + nucleotide

 1ygw]] - AoRNase T1 – NMR

RNase U2

3agn]], 3ago, 3ahw - UsRNase U2 + AMP]] - Ustilago sphaerogena
 1rtu]] - UsRNase U2

RNase U2B

3ahs]] - UsRNase U2B

RNase Z

2e7y]] - TmRNase Z 2fk6]] - BsRNase Z (mutant) + tRNA Thr 
 1y44]] - BsRNase Z (mutant)

Oligoribonuclease

2igi]], [[1yta – EcORNase 
2gbz]] - ORNase]] - Xanthomonas campestris 
1j9a]] - ORNase]] - Haemophilus influenzae

Polynucleotide Phosphorylase

3cdi]] - EcPNPase 3gll]] - EcPNPase core 3cdj]] - EcPNPase C-terminal truncated 1e3h]], 1e3p - PNPase]] - Streptomyces antibioticus 3gcm]], 3gme, 3h1c - EcPNPase + RNase E recognition domain 3h36]] - PNPase fragment]] - Streptococcus mutans

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