Non-polymerizable monomeric actin

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<table width='450' align='right' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#d0d0d0'><applet load='Image:Multistate temp.pdb' size='450' frame='true' align='right' scene='User:Thomas_E_Sladewski/Sandbox_1/Temp1_test_scene6/1' /></td></tr><tr><td bgcolor='#d0d0d0'>Morph of the [[lac repressor]] complexed with DNA showing the differences between non-specific binding (straight DNA) vs. specific recognition of the operator sequence (kinked DNA). Whether the binding kinks the DNA, or simply stabilizes a pre-existing kink, is unknown. [[Lac repressor#Specific Binding|Details]].</td></tr></table>
<table width='450' align='right' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#d0d0d0'><applet load='Image:Multistate temp.pdb' size='450' frame='true' align='right' scene='User:Thomas_E_Sladewski/Sandbox_1/Temp1_test_scene6/1' /></td></tr><tr><td bgcolor='#d0d0d0'>Morph of the [[lac repressor]] complexed with DNA showing the differences between non-specific binding (straight DNA) vs. specific recognition of the operator sequence (kinked DNA). Whether the binding kinks the DNA, or simply stabilizes a pre-existing kink, is unknown. [[Lac repressor#Specific Binding|Details]].</td></tr></table>
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<table width='450' align='right' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#d0d0d0'><applet load='Image:Multistate temp.pdb' size='450' align='right' scene='User:Thomas_E_Sladewski/Sandbox_1/Temp1_test_scene6/1' /></td></tr><tr><td bgcolor='#d0d0d0'>Morph of the [[lac repressor]] complexed with DNA showing the differences between non-specific binding (straight DNA) vs. specific recognition of the operator sequence (kinked DNA). Whether the binding kinks the DNA, or simply stabilizes a pre-existing kink, is unknown. [[Lac repressor#Specific Binding|Details]].</td></tr></table>
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<table width='450' align='right' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#d0d0d0'><applet load=Image:2HF3 2HF4 10state morph4.pdb' size='450' align='right' scene='User:Thomas_E_Sladewski/Sandbox_1/10state_morph_scene1/1' /></td></tr><tr><td bgcolor='#d0d0d0'>Morph of the [[lac repressor]] complexed with DNA showing the differences between non-specific binding (straight DNA) vs. specific recognition of the operator sequence (kinked DNA). Whether the binding kinks the DNA, or simply stabilizes a pre-existing kink, is unknown. [[Lac repressor#Specific Binding|Details]].</td></tr></table>

Revision as of 02:33, 3 April 2011

 
Drag the structure with the mouse to rotate
Morph of the lac repressor complexed with DNA showing the differences between non-specific binding (straight DNA) vs. specific recognition of the operator sequence (kinked DNA). Whether the binding kinks the DNA, or simply stabilizes a pre-existing kink, is unknown. Details.
 
Drag the structure with the mouse to rotate
Morph of the lac repressor complexed with DNA showing the differences between non-specific binding (straight DNA) vs. specific recognition of the operator sequence (kinked DNA). Whether the binding kinks the DNA, or simply stabilizes a pre-existing kink, is unknown. Details.


Contents

Crystal structure of Monomeric Actin in its ATP-bound state

About this Structure

This is where I will add my text. 2hf4 is a 1 chain structure of Actin with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

See Also

Reference

  • Rould MA, Wan Q, Joel PB, Lowey S, Trybus KM. Crystal structures of expressed non-polymerizable monomeric actin in the ADP and ATP states. J Biol Chem. 2006 Oct 20;281(42):31909-19. Epub 2006 Aug 18. PMID:16920713 doi:M601973200

Proteopedia Page Contributors and Editors (what is this?)

Thomas E Sladewski, Michal Harel, Alexander Berchansky

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