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Virus protease
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(New page: Crystal Structure of HIV-1 protease 1odw {{STRUCTURE_1odw| PDB=1odw | SIZE=300| S |right|CAPTION=HIV-1 protease 1odw }} '''Virus proteases''...)
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Revision as of 10:33, 4 April 2011
Image:1odw.png
Crystal Structure of HIV-1 protease 1odw
Virus proteases include HIV protease, XMRV protease, retropepsin. HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa.
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3D Structures of Virus proteases
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Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
