2xxh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2xxh is ON HOLD Authors: Ward, S.E., Harries, M., Aldegheri, L., Austin, N.E., Ballantine, S., Ballini, E., Bradley, D.M., Bax, B.D., Clarke, B.P., ...) |
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| - | + | [[Image:2xxh.jpg|left|200px]] | |
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| + | {{STRUCTURE_2xxh| PDB=2xxh | SCENE= }} | ||
| - | + | ===CRYSTAL STRUCTURE OF 1-(4-(2-OXO-2-(1-PYRROLIDINYL)ETHYL)PHENYL)-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 1.5A RESOLUTION.=== | |
| - | Description: Crystal structure of 1-(4-(2-oxo-2-(1-pyrrolidinyl)ethyl)phenyl)-3-( trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 1.5A resolution. | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_21128618}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21128618 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21128618}} | ||
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| + | ==About this Structure== | ||
| + | [[2xxh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XXH OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:21128618</ref><references group="xtra"/> | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Aldegheri, L.]] | ||
| + | [[Category: Austin, N E.]] | ||
| + | [[Category: Ballantine, S.]] | ||
| + | [[Category: Ballini, E.]] | ||
| + | [[Category: Bax, B D.]] | ||
| + | [[Category: Bradley, D M.]] | ||
| + | [[Category: Clarke, B P.]] | ||
| + | [[Category: Dalnegro, G.]] | ||
| + | [[Category: Harries, M.]] | ||
| + | [[Category: Harris, A J.]] | ||
| + | [[Category: Harrison, S A.]] | ||
| + | [[Category: Melarange, R A.]] | ||
| + | [[Category: Mookherjee, C.]] | ||
| + | [[Category: Mosley, J.]] | ||
| + | [[Category: Oliosi, B.]] | ||
| + | [[Category: Smith, K J.]] | ||
| + | [[Category: Thewlis, K M.]] | ||
| + | [[Category: Ward, S E.]] | ||
| + | [[Category: Woollard, P M.]] | ||
| + | [[Category: Yusaf, S P.]] | ||
Revision as of 08:56, 6 April 2011
CRYSTAL STRUCTURE OF 1-(4-(2-OXO-2-(1-PYRROLIDINYL)ETHYL)PHENYL)-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 1.5A RESOLUTION.
Template:ABSTRACT PUBMED 21128618
About this Structure
2xxh is a 3 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Ward SE, Harries M, Aldegheri L, Austin NE, Ballantine S, Ballini E, Bradley DM, Bax BD, Clarke BP, Harris AJ, Harrison SA, Melarange RA, Mookherjee C, Mosley J, Dal Negro G, Oliosi B, Smith KJ, Thewlis KM, Woollard PM, Yusaf SP. Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators. J Med Chem. 2010 Dec 3. PMID:21128618 doi:10.1021/jm100679e
Categories: Rattus norvegicus | Aldegheri, L. | Austin, N E. | Ballantine, S. | Ballini, E. | Bax, B D. | Bradley, D M. | Clarke, B P. | Dalnegro, G. | Harries, M. | Harris, A J. | Harrison, S A. | Melarange, R A. | Mookherjee, C. | Mosley, J. | Oliosi, B. | Smith, K J. | Thewlis, K M. | Ward, S E. | Woollard, P M. | Yusaf, S P.
