3qkm

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'''Unreleased structure'''
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[[Image:3qkm.jpg|left|200px]]
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The entry 3qkm is ON HOLD until Paper Publication
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{{STRUCTURE_3qkm| PDB=3qkm | SCENE= }}
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Authors: Xu, R., Banka, A., Blake, J.F., Mitchell, I.S., Wallace, E.M., Gloor, S.L., Martinson, M., Risom, T., Gross, S.D., Morales, T., Vigers, G.P.A., Brandhuber, B.J., Skelton, N.J.
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===Spirocyclic sulfonamides as AKT inhibitors===
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Description: Spirocyclic sulfonamides as AKT inhibitors
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{{ABSTRACT_PUBMED_21420856}}
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==About this Structure==
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[[3qkm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKM OCA].
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==Reference==
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<ref group="xtra">PMID:21420856</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Banka, A.]]
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[[Category: Blake, J F.]]
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[[Category: Brandhuber, B J.]]
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[[Category: Gloor, S L.]]
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[[Category: Gross, S D.]]
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[[Category: Martinson, M.]]
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[[Category: Mitchell, I S.]]
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[[Category: Morales, T.]]
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[[Category: Risom, T.]]
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[[Category: Skelton, N J.]]
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[[Category: Vigers, G P.A.]]
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[[Category: Wallace, E M.]]
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[[Category: Xu, R.]]

Revision as of 09:01, 6 April 2011

Image:3qkm.jpg

Template:STRUCTURE 3qkm

Spirocyclic sulfonamides as AKT inhibitors

Template:ABSTRACT PUBMED 21420856

About this Structure

3qkm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Xu R, Banka A, Blake JF, Mitchell IS, Wallace EM, Bencsik JR, Kallan NC, Spencer KL, Gloor SL, Martinson M, Risom T, Gross SD, Morales TH, Wu WI, Vigers GP, Brandhuber BJ, Skelton NJ. Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2335-40. Epub 2011 Feb 26. PMID:21420856 doi:10.1016/j.bmcl.2011.02.098

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OCA

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