3qkm
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | + | [[Image:3qkm.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3qkm", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
+ | or leave the SCENE parameter empty for the default display. | ||
+ | --> | ||
+ | {{STRUCTURE_3qkm| PDB=3qkm | SCENE= }} | ||
- | + | ===Spirocyclic sulfonamides as AKT inhibitors=== | |
- | + | ||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21420856}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21420856 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_21420856}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3qkm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKM OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:21420856</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Non-specific serine/threonine protein kinase]] | ||
+ | [[Category: Banka, A.]] | ||
+ | [[Category: Blake, J F.]] | ||
+ | [[Category: Brandhuber, B J.]] | ||
+ | [[Category: Gloor, S L.]] | ||
+ | [[Category: Gross, S D.]] | ||
+ | [[Category: Martinson, M.]] | ||
+ | [[Category: Mitchell, I S.]] | ||
+ | [[Category: Morales, T.]] | ||
+ | [[Category: Risom, T.]] | ||
+ | [[Category: Skelton, N J.]] | ||
+ | [[Category: Vigers, G P.A.]] | ||
+ | [[Category: Wallace, E M.]] | ||
+ | [[Category: Xu, R.]] |
Revision as of 09:01, 6 April 2011
Spirocyclic sulfonamides as AKT inhibitors
Template:ABSTRACT PUBMED 21420856
About this Structure
3qkm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Xu R, Banka A, Blake JF, Mitchell IS, Wallace EM, Bencsik JR, Kallan NC, Spencer KL, Gloor SL, Martinson M, Risom T, Gross SD, Morales TH, Wu WI, Vigers GP, Brandhuber BJ, Skelton NJ. Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2335-40. Epub 2011 Feb 26. PMID:21420856 doi:10.1016/j.bmcl.2011.02.098