Samantha Stone Sandbox
From Proteopedia
(Difference between revisions)
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| - | The following picture shows the M1-M10 helices that are involved sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA). The M1 helix has a kink that is a part of all P-type ATPases. This kink is involved in cytoplasmic cation access pathway | + | The following picture shows the M1-M10 helices that are involved sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA). The M1 helix has a kink that is a part of all P-type ATPases. This kink is involved in cytoplasmic cation access pathway. The metal ion needed for binding can also be seen. |
http://www.jbc.org/content/284/20/13513/F1.large.jpg | http://www.jbc.org/content/284/20/13513/F1.large.jpg | ||
Revision as of 20:08, 20 April 2011
This is the 3FPB Membrane Protein.
Its structure consists of ATP, adenosine 5'-(beta,gamma-methylene)triphosphate (AMPPCP), and cyclopiazonic acid (CZA). A metal (Mg or Mn) must react in the ATP binding site for CZA to bind and react. This occurs at the M1 helix.
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| 3cin, resolution 1.70Å () | |||||||||
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| Ligands: | , , | ||||||||
| Gene: | TM1419, TM_1419 (Thermotoga maritima MSB8) | ||||||||
| Activity: | Inositol-3-phosphate synthase, with EC number 5.5.1.4 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum, TOPSAN | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
The following picture shows the M1-M10 helices that are involved sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA). The M1 helix has a kink that is a part of all P-type ATPases. This kink is involved in cytoplasmic cation access pathway. The metal ion needed for binding can also be seen.
