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3qtf

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[[Image:3qtf.jpg|left|200px]]
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Revision as of 10:05, 21 April 2011

Template:STRUCTURE 3qtf

Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity

Template:ABSTRACT PUBMED 21420297

About this Structure

3qtf is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zapf CW, Bloom JD, McBean JL, Dushin RG, Nittoli T, Ingalls C, Sutherland AG, Sonye JP, Eid CN, Golas J, Liu H, Boschelli F, Hu Y, Vogan E, Levin JI. Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2278-82. Epub 2011 Feb 28. PMID:21420297 doi:10.1016/j.bmcl.2011.02.101

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