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User:Momodou L. Jammeh/Sandbox 1
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===INTRODUCTION=== | ===INTRODUCTION=== | ||
| - | + | Transcription is the process of mRNA synthesis by RNA polymerase, an enzyme that uses a strand of DNA as a template for ribonucloetide addition. During this process, RNA polymerase encounters several regulatory proteins, called transcription factors, that effect transcription in various ways. One of the major regulatory activities of transcription regulators is terminating the process at specific sites in the DNA. In ''E. coli'', transcription is terminated through rho dependent and independent mechanisms. Rho dependent transcription requires a helicase protein called rho factor. Rho factor has helicase activity as it functions by moving on the new mRNA strand toward the RNA polymerase, DNA and RNA complex whose dissociation results in the termination of transcription. Rho uses energy derived from its ATPase mechanism (hydrolysis of ATP into ADP and pyrophosphate) to drive its movement along the newly formed RNA molecule toward the elongation complex to be dissociated. | |
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| - | Transcription is the process of mRNA synthesis by RNA polymerase, an enzyme that uses a strand of DNA as a template for ribonucloetide addition. During this process, RNA polymerase encounters several regulatory proteins, called transcription factors, that effect transcription in various ways. One of the major regulatory activities of transcription regulators is terminating the process at specific sites in the DNA. In ''E. coli'', transcription is terminated through rho dependent and independent mechanisms. Rho dependent transcription requires a | + | |
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Revision as of 04:52, 23 April 2011
Contents |
RHO TERMINATION FACTOR
INTRODUCTION
Transcription is the process of mRNA synthesis by RNA polymerase, an enzyme that uses a strand of DNA as a template for ribonucloetide addition. During this process, RNA polymerase encounters several regulatory proteins, called transcription factors, that effect transcription in various ways. One of the major regulatory activities of transcription regulators is terminating the process at specific sites in the DNA. In E. coli, transcription is terminated through rho dependent and independent mechanisms. Rho dependent transcription requires a helicase protein called rho factor. Rho factor has helicase activity as it functions by moving on the new mRNA strand toward the RNA polymerase, DNA and RNA complex whose dissociation results in the termination of transcription. Rho uses energy derived from its ATPase mechanism (hydrolysis of ATP into ADP and pyrophosphate) to drive its movement along the newly formed RNA molecule toward the elongation complex to be dissociated.
HISTORY
STRUCTURE
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