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User:Momodou L. Jammeh/Sandbox 1
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===INTRODUCTION=== | ===INTRODUCTION=== | ||
| - | Transcription is the process of mRNA synthesis by RNA polymerase, an enzyme that uses a strand of DNA as a template for ribonucloetide addition. During this process, RNA polymerase encounters several regulatory proteins, called transcription factors, that effect transcription in various ways. One of the major regulatory activities of transcription regulators is terminating the process at specific sites in the DNA. In ''E. coli'', transcription is terminated through rho dependent and independent mechanisms. Rho dependent transcription requires a helicase protein called rho factor. Rho factor | + | Transcription is the process of mRNA synthesis by RNA polymerase, an enzyme that uses a strand of DNA as a template for ribonucloetide addition. During this process, RNA polymerase encounters several regulatory proteins, called transcription factors, that effect transcription in various ways. One of the major regulatory activities of transcription regulators is terminating the process at specific sites in the DNA. In ''E. coli'', transcription is terminated through rho dependent and independent mechanisms. Rho dependent transcription requires a helicase protein called rho factor. Rho factor belongs in the helicase class of enzymes because it is a motor protein that functions through directional movement on the new mRNA strand toward the RNA polymerase, DNA and RNA complex (elongation complex) whose dissociation results in the termination of transcription. It uses energy derived from its ATPase mechanism (hydrolysis of ATP into ADP and pyrophosphate) to drive its movement along the newly formed RNA molecule toward the elongation complex to be dissociated. |
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Revision as of 05:00, 23 April 2011
Contents |
RHO TERMINATION FACTOR
INTRODUCTION
Transcription is the process of mRNA synthesis by RNA polymerase, an enzyme that uses a strand of DNA as a template for ribonucloetide addition. During this process, RNA polymerase encounters several regulatory proteins, called transcription factors, that effect transcription in various ways. One of the major regulatory activities of transcription regulators is terminating the process at specific sites in the DNA. In E. coli, transcription is terminated through rho dependent and independent mechanisms. Rho dependent transcription requires a helicase protein called rho factor. Rho factor belongs in the helicase class of enzymes because it is a motor protein that functions through directional movement on the new mRNA strand toward the RNA polymerase, DNA and RNA complex (elongation complex) whose dissociation results in the termination of transcription. It uses energy derived from its ATPase mechanism (hydrolysis of ATP into ADP and pyrophosphate) to drive its movement along the newly formed RNA molecule toward the elongation complex to be dissociated.
HISTORY
STRUCTURE
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