This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2jmx
From Proteopedia
(New page: 200px<br /><applet load="2jmx" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jmx" /> '''OSCP-NT (1-120) in complex with N-terminal (...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:2jmx.gif|left|200px]]<br /><applet load="2jmx" size=" | + | [[Image:2jmx.gif|left|200px]]<br /><applet load="2jmx" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2jmx" /> | caption="2jmx" /> | ||
'''OSCP-NT (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase'''<br /> | '''OSCP-NT (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase'''<br /> | ||
| Line 7: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2JMX is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Active as [http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] Full crystallographic information is available from [http:// | + | 2JMX is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Active as [http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMX OCA]. |
==Reference== | ==Reference== | ||
| Line 23: | Line 23: | ||
[[Category: oscp-nt alpha-nt complex]] | [[Category: oscp-nt alpha-nt complex]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 15:35:22 2008'' |
Revision as of 13:35, 23 January 2008
|
OSCP-NT (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase
Overview
The peripheral stalk of ATP synthase acts as a stator holding the, alpha(3)beta(3) catalytic subcomplex and the membrane subunit a against, the torque of the rotating central stalk and attached c ring. In bovine, mitochondria, the N-terminal domain of the oligomycin sensitivity, conferral protein (OSCP-NT; residues 1-120) anchors one end of the, peripheral stalk to the N-terminal tails of one or more alpha subunits of, the F(1) subcomplex. Here, we present an NMR characterisation of the, interaction between OSCP-NT and a peptide corresponding to residues 1-25, of the alpha-subunit of bovine F(1)-ATPase. The interaction site contains, adjoining hydrophobic surfaces of helices 1 and 5 of OSCP-NT binding to, hydrophobic side-chains of the alpha-peptide.
About this Structure
2JMX is a Protein complex structure of sequences from Bos taurus. Active as H(+)-transporting two-sector ATPase, with EC number 3.6.3.14 Full crystallographic information is available from OCA.
Reference
How the N-terminal Domain of the OSCP Subunit of Bovine F(1)F(o)-ATP Synthase Interacts with the N-terminal Region of an Alpha Subunit., Carbajo RJ, Kellas FA, Yang JC, Runswick MJ, Montgomery MG, Walker JE, Neuhaus D, J Mol Biol. 2007 Apr 27;368(2):310-8. Epub 2007 Feb 22. PMID:17355883
Page seeded by OCA on Wed Jan 23 15:35:22 2008
