3o23

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'''Unreleased structure'''
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[[Image:3o23.jpg|left|200px]]
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The entry 3o23 is ON HOLD until Paper Publication
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{{STRUCTURE_3o23| PDB=3o23 | SCENE= }}
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Authors: Maignan, S., Guilloteau, J.P., Dupuy, A.
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===Human unphosphorylated IGF1-R Kinase domain in complex with an hydantoin inhibitor===
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Description: Human bisphosphorylated IGF1-R Kinase domain (2P) in complex with an hydantoin inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:35:01 2010''
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{{ABSTRACT_PUBMED_21441024}}
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==About this Structure==
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[[3o23]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O23 OCA].
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==Reference==
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<ref group="xtra">PMID:021441024</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Dupuy, A.]]
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[[Category: Guilloteau, J P.]]
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[[Category: Maignan, S.]]

Revision as of 06:52, 4 May 2011

Template:STRUCTURE 3o23

Human unphosphorylated IGF1-R Kinase domain in complex with an hydantoin inhibitor

Template:ABSTRACT PUBMED 21441024

About this Structure

3o23 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lesuisse D, Mauger J, Nemecek C, Maignan S, Boiziau J, Harlow G, Hittinger A, Ruf S, Strobel H, Nair A, Ritter K, Malleron JL, Dagallier A, El-Ahmad Y, Guilloteau JP, Guizani H, Bouchard H, Venot C. Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: Advantages in comparison with competitive inhibitors. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2224-8. Epub 2011 Mar 4. PMID:21441024 doi:10.1016/j.bmcl.2011.03.003

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