1gyy
From Proteopedia
(New page: 200px<br /> <applet load="1gyy" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gyy, resolution 1.35Å" /> '''THE CRYSTAL STRUCTU...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1GYY is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with FHC as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.2.1 5.3.2.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GYY OCA]]. | + | 1GYY is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with FHC as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Phenylpyruvate_tautomerase Phenylpyruvate tautomerase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.2.1 5.3.2.1]]. Structure known Active Site: FHA. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GYY OCA]]. |
==Reference== | ==Reference== | ||
The crystal structure of YdcE, a 4-oxalocrotonate tautomerase homologue from Escherichia coli, confirms the structural basis for oligomer diversity., Almrud JJ, Kern AD, Wang SC, Czerwinski RM, Johnson WH Jr, Murzin AG, Hackert ML, Whitman CP, Biochemistry. 2002 Oct 8;41(40):12010-24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12356301 12356301] | The crystal structure of YdcE, a 4-oxalocrotonate tautomerase homologue from Escherichia coli, confirms the structural basis for oligomer diversity., Almrud JJ, Kern AD, Wang SC, Czerwinski RM, Johnson WH Jr, Murzin AG, Hackert ML, Whitman CP, Biochemistry. 2002 Oct 8;41(40):12010-24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12356301 12356301] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| + | [[Category: Phenylpyruvate tautomerase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Almrud, J.]] | [[Category: Almrud, J.]] | ||
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[[Category: tautomerase]] | [[Category: tautomerase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:58:57 2007'' |
Revision as of 09:54, 30 October 2007
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THE CRYSTAL STRUCTURE OF YDCE, A 4-OXALOCROTONATE TAUTOMERASE HOMOLOGUE FROM ESCHERICHIA COLI, CONFIRMS THE STRUCTURAL BASIS FOR OLIGOMER DIVERSITY
Overview
The tautomerase superfamily consists of three major families represented, by 4-oxalocrotonate tautomerase (4-OT), 5-(carboxymethyl)-2-hydroxymuconate isomerase (CHMI), and macrophage, migration inhibitory factor (MIF). The members of this superfamily are, structurally homologous proteins constructed from a simple beta-alpha-beta, fold that share a key mechanistic feature; they use an amino-terminal, proline, which has an unusually low pK(a), as the general base in a, keto-enol tautomerization. Several new members of the 4-OT family have now, been identified using PSI-BLAST and categorized into five subfamilies on, the basis of multiple-sequence alignments and the conservation of key, catalytic and structural residues. The members of subfamily 5, which, includes a hypothetical protein ... [(full description)]
About this Structure
1GYY is a [Single protein] structure of sequence from [Escherichia coli] with FHC as [ligand]. Active as [Phenylpyruvate tautomerase], with EC number [5.3.2.1]. Structure known Active Site: FHA. Full crystallographic information is available from [OCA].
Reference
The crystal structure of YdcE, a 4-oxalocrotonate tautomerase homologue from Escherichia coli, confirms the structural basis for oligomer diversity., Almrud JJ, Kern AD, Wang SC, Czerwinski RM, Johnson WH Jr, Murzin AG, Hackert ML, Whitman CP, Biochemistry. 2002 Oct 8;41(40):12010-24. PMID:12356301
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