1gyc
From Proteopedia
(New page: 200px<br /> <applet load="1gyc" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gyc, resolution 1.9Å" /> '''CRYSTAL STRUCTURE DE...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1GYC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Trametes_versicolor Trametes versicolor]] with NAG, CU and IPA as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GYC OCA]]. | + | 1GYC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Trametes_versicolor Trametes versicolor]] with NAG, CU and IPA as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Laccase Laccase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2]]. Structure known Active Site: CU1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GYC OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of a laccase from the fungus Trametes versicolor at 1.90-A resolution containing a full complement of coppers., Piontek K, Antorini M, Choinowski T, J Biol Chem. 2002 Oct 4;277(40):37663-9. Epub 2002 Aug 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12163489 12163489] | Crystal structure of a laccase from the fungus Trametes versicolor at 1.90-A resolution containing a full complement of coppers., Piontek K, Antorini M, Choinowski T, J Biol Chem. 2002 Oct 4;277(40):37663-9. Epub 2002 Aug 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12163489 12163489] | ||
| + | [[Category: Laccase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Trametes versicolor]] | [[Category: Trametes versicolor]] | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:59:10 2007'' |
Revision as of 09:54, 30 October 2007
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CRYSTAL STRUCTURE DETERMINATION AT ROOM TEMPERATURE OF A LACCASE FROM TRAMETES VERSICOLOR IN ITS OXIDISED FORM CONTAINING A FULL COMPLEMENT OF COPPER IONS
Overview
Laccase is a polyphenol oxidase, which belongs to the family of blue, multicopper oxidases. These enzymes catalyze the one-electron oxidation of, four reducing-substrate molecules concomitant with the four-electron, reduction of molecular oxygen to water. Laccases oxidize a broad range of, substrates, preferably phenolic compounds. In the presence of mediators, fungal laccases exhibit an enlarged substrate range and are then able to, oxidize compounds with a redox potential exceeding their own. Until now, only one crystal structure of a laccase in an inactive, type-2, copper-depleted form has been reported. We present here the first crystal, structure of an active laccase containing a full complement of coppers, the complete polypeptide chain together with seven carbohydrate moieties., ... [(full description)]
About this Structure
1GYC is a [Single protein] structure of sequence from [Trametes versicolor] with NAG, CU and IPA as [ligands]. Active as [Laccase], with EC number [1.10.3.2]. Structure known Active Site: CU1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of a laccase from the fungus Trametes versicolor at 1.90-A resolution containing a full complement of coppers., Piontek K, Antorini M, Choinowski T, J Biol Chem. 2002 Oct 4;277(40):37663-9. Epub 2002 Aug 5. PMID:12163489
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