1gyt
From Proteopedia
(New page: 200px<br /> <applet load="1gyt" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gyt, resolution 2.5Å" /> '''E. COLI AMINOPEPTIDA...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1GYT is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with ZN, CO3 and CL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.1 3.4.11.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GYT OCA]]. | + | 1GYT is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with ZN, CO3 and CL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Leucyl_aminopeptidase Leucyl aminopeptidase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.1 3.4.11.1]]. Structure known Active Site: ZA1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GYT OCA]]. |
==Reference== | ==Reference== | ||
X-ray structure of aminopeptidase A from Escherichia coli and a model for the nucleoprotein complex in Xer site-specific recombination., Strater N, Sherratt DJ, Colloms SD, EMBO J. 1999 Aug 16;18(16):4513-22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10449417 10449417] | X-ray structure of aminopeptidase A from Escherichia coli and a model for the nucleoprotein complex in Xer site-specific recombination., Strater N, Sherratt DJ, Colloms SD, EMBO J. 1999 Aug 16;18(16):4513-22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10449417 10449417] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| + | [[Category: Leucyl aminopeptidase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Straeter, N.]] | [[Category: Straeter, N.]] | ||
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[[Category: peptidase]] | [[Category: peptidase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:59:28 2007'' |
Revision as of 09:54, 30 October 2007
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E. COLI AMINOPEPTIDASE A (PEPA)
Overview
The structure of aminopeptidase A (PepA), which functions as a DNA-binding, protein in Xer site-specific recombination and in transcriptional control, of the carAB operon in Escherichia coli, has been determined at 2.5 A, resolution. In Xer recombination at cer, PepA and the arginine repressor, (ArgR) serve as accessory proteins, ensuring that recombination is, exclusively intramolecular. In contrast, PepA homologues from other, species have no known DNA-binding activity and are not implicated in, transcriptional regulation or control of site-specific recombination. PepA, comprises two domains, which have similar folds to the two domains of, bovine lens leucine aminopeptidase (LAP). However, the N-terminal domain, of PepA, which probably plays a significant role in DNA binding, is, ... [(full description)]
About this Structure
1GYT is a [Single protein] structure of sequence from [Escherichia coli] with ZN, CO3 and CL as [ligands]. Active as [Leucyl aminopeptidase], with EC number [3.4.11.1]. Structure known Active Site: ZA1. Full crystallographic information is available from [OCA].
Reference
X-ray structure of aminopeptidase A from Escherichia coli and a model for the nucleoprotein complex in Xer site-specific recombination., Strater N, Sherratt DJ, Colloms SD, EMBO J. 1999 Aug 16;18(16):4513-22. PMID:10449417
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