Thiolase
From Proteopedia
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| + | ===3-ketoacyl-CoA thiolase=== | ||
| + | [[2wu9]], [[2c7y]], [[2c7z]] – KCT peroxisomal residues 36-462 – Arabidopsis thaliana<br /> | ||
| + | [[2wua]] - KCT peroxisomal residues 17-449 (mutant) – sunflower<br /> | ||
| + | [[2iik]] – hKCT peroximal]] - human<br /> | ||
| + | [[3goa]] – KCT – Salmonella typhimurium<br /> | ||
| + | [[1afw]], [[1pxt]] – KCT peroxisomal]] - yeast<br /> | ||
| + | [[2d3t]] – PfKCT + fatty oxidation complex β subunit – Pseudomonas fragi<br /> | ||
| + | [[1wdk]], [[1wdl]], [[1wdm]] - PfKCT + fatty oxidation complex α subunit | ||
| + | |||
| + | ===Acetoacetyl-CoA thiolase=== | ||
| + | |||
| + | [[1m4s]], [[1m4t]], [[1dlu]], [[1qfl]] - ZrACT – Zoogloea ramigera<br /> | ||
| + | [[1dm3]], [[1dlv]] – ZrACT + CoA<br /> | ||
| + | [[2wku]], [[2wl6]], [[1m1t]], [[1m3k]] - ZrACT (mutant) <br /> | ||
| + | [[2wkt]], [[2wkv]], [[2wl4]], [[2wl5]], [[2vtz]], [[2vu0]], [[1m3z]] – ZrACT (mutant) + CoA<br /> | ||
| + | [[1m1o]] - ZrACT (mutant) + acetoacetyl-CoA<br /> | ||
| + | [[2vu0]], [[1nl7]] - ZrACT + CoA<br /> | ||
| + | [[2vu1]], [[2vu2]], [[1ou6]] - ZrACT + pantheteine-11-pivalate<br /> | ||
| + | [[2ib7]], [[2ib8]], [[2ib9]], [[2ibu]], [[2ibw]], [[2iby]], [[2f2s]] – hACT mitochondrial<br /> | ||
| + | [[1wl5]] - hACT cytosolic<br /> | ||
| + | [[1wl4]] – hACT cytosolic + CoA<br /> | ||
Revision as of 10:06, 11 May 2011
Thiolase involves two different thiolases . The 3-ketoacyl-CoA thiolase (KCT) is involved in fatty acid β oxidation. Acetoacetyl-CoA thiolase (ACT) is involved in the thiolysis of acetoacetyl-CoA.
3D Structures of Thiolase
3-ketoacyl-CoA thiolase
2wu9, 2c7y, 2c7z – KCT peroxisomal residues 36-462 – Arabidopsis thaliana
2wua - KCT peroxisomal residues 17-449 (mutant) – sunflower
2iik – hKCT peroximal]] - human
3goa – KCT – Salmonella typhimurium
1afw, 1pxt – KCT peroxisomal]] - yeast
2d3t – PfKCT + fatty oxidation complex β subunit – Pseudomonas fragi
1wdk, 1wdl, 1wdm - PfKCT + fatty oxidation complex α subunit
Acetoacetyl-CoA thiolase
1m4s, 1m4t, 1dlu, 1qfl - ZrACT – Zoogloea ramigera
1dm3, 1dlv – ZrACT + CoA
2wku, 2wl6, 1m1t, 1m3k - ZrACT (mutant)
2wkt, 2wkv, 2wl4, 2wl5, 2vtz, 2vu0, 1m3z – ZrACT (mutant) + CoA
1m1o - ZrACT (mutant) + acetoacetyl-CoA
2vu0, 1nl7 - ZrACT + CoA
2vu1, 2vu2, 1ou6 - ZrACT + pantheteine-11-pivalate
2ib7, 2ib8, 2ib9, 2ibu, 2ibw, 2iby, 2f2s – hACT mitochondrial
1wl5 - hACT cytosolic
1wl4 – hACT cytosolic + CoA
