2yac

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===CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH NMS-P937===
===CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH NMS-P937===
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{{ABSTRACT_PUBMED_21470862}}
==About this Structure==
==About this Structure==
[[2yac]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAC OCA].
[[2yac]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAC OCA].
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==Reference==
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<ref group="xtra">PMID:021470862</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Polo kinase]]
[[Category: Polo kinase]]
[[Category: Bertrand, J A.]]
[[Category: Bertrand, J A.]]
[[Category: Bossi, R T.]]
[[Category: Bossi, R T.]]

Revision as of 03:54, 12 May 2011

Template:STRUCTURE 2yac

CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH NMS-P937

Template:ABSTRACT PUBMED 21470862

About this Structure

2yac is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Beria I, Bossi RT, Brasca MG, Caruso M, Ceccarelli W, Fachin G, Fasolini M, Forte B, Fiorentini F, Pesenti E, Pezzetta D, Posteri H, Scolaro A, Depaolini SR, Valsasina B. NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor. Bioorg Med Chem Lett. 2011 May 15;21(10):2969-74. Epub 2011 Mar 21. PMID:21470862 doi:10.1016/j.bmcl.2011.03.054

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