3pj8

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==Reference==
==Reference==
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<ref group="xtra">PMID:21417417</ref><references group="xtra"/>
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<ref group="xtra">PMID:021417417</ref><references group="xtra"/>
[[Category: Cyclin-dependent kinase]]
[[Category: Cyclin-dependent kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 04:00, 12 May 2011

Template:STRUCTURE 3pj8

Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.

Template:ABSTRACT PUBMED 21417417

About this Structure

3pj8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jorda R, Havlicek L, McNae IW, Walkinshaw MD, Voller J, Sturc A, Navratilova J, Kuzma M, Mistrik M, Bartek J, Strnad M, Krystof V. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-dependent Kinases with Antiproliferative Activity. J Med Chem. 2011 Mar 21. PMID:21417417 doi:10.1021/jm200064p

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