2x7o

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Image:2x7o.png

Template:STRUCTURE 2x7o

CRYSTAL STRUCTURE OF TGFBRI COMPLEXED WITH AN INDOLINONE INHIBITOR

Template:ABSTRACT PUBMED 20919678

About this Structure

2x7o is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Roth GJ, Heckel A, Brandl T, Grauert M, Hoerer S, Kley JT, Schnapp G, Baum P, Mennerich D, Schnapp A, Park JE. Design, Synthesis, and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor beta Receptor I (TGFbetaRI). J Med Chem. 2010 Oct 4. PMID:20919678 doi:10.1021/jm100812a

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OCA

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