3msl

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[[Image:3msl.png|left|200px]]
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==About this Structure==
==About this Structure==
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3MSL is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSL OCA].
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[[3msl]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSL OCA].
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==See Also==
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*[[Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20656487</ref><references group="xtra"/>
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<ref group="xtra">PMID:020656487</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Madden, J.]]
[[Category: Madden, J.]]
[[Category: Smith, M.]]
[[Category: Smith, M.]]
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[[Category: Alzheimer's disease]]
 
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[[Category: Amyloid precursor protein secretase]]
 
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[[Category: Aspartic endopeptidase]]
 
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[[Category: Aspartic protease]]
 
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[[Category: Aspartyl protease]]
 
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[[Category: Base]]
 
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[[Category: Beta-secretase]]
 
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[[Category: Fluorescence polarisation]]
 
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[[Category: Fragment-based drug design]]
 
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[[Category: Glycoprotein]]
 
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[[Category: Hydrolase]]
 
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[[Category: Memapsin 2]]
 
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[[Category: Protease]]
 
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[[Category: Transmembrane]]
 
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[[Category: Zymogen]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:21:26 2010''
 

Revision as of 05:57, 25 May 2011

Template:STRUCTURE 3msl

Contents

Fragment Based Discovery and Optimisation of BACE-1 Inhibitors

Template:ABSTRACT PUBMED 20656487

About this Structure

3msl is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089

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