3msl

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Revision as of 05:57, 25 May 2011

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Template:STRUCTURE 3msl

Contents 1 Fragment Based Discovery and Optimisation of BACE-1 Inhibitors 2 About this Structure 3 See Also 4 Reference

Fragment Based Discovery and Optimisation of BACE-1 Inhibitors

Template:ABSTRACT PUBMED 20656487

About this Structure

3msl is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089