This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3msm
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3msm.png|left|200px]] | [[Image:3msm.png|left|200px]] | ||
| Line 20: | Line 19: | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3msm]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSM OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020656487</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
| Line 32: | Line 34: | ||
[[Category: Madden, J.]] | [[Category: Madden, J.]] | ||
[[Category: Smith, M A.]] | [[Category: Smith, M A.]] | ||
| - | [[Category: Alzheimer's disease]] | ||
| - | [[Category: Amyloid precursor protein secretase]] | ||
| - | [[Category: Aspartic endopeptidase]] | ||
| - | [[Category: Aspartic protease]] | ||
| - | [[Category: Aspartyl protease]] | ||
| - | [[Category: Base]] | ||
| - | [[Category: Beta-secretase]] | ||
| - | [[Category: Fluorescence polarisation]] | ||
| - | [[Category: Fragment-based drug design]] | ||
| - | [[Category: Glycoprotein]] | ||
| - | [[Category: Hydrolase]] | ||
| - | [[Category: Memapsin 2]] | ||
| - | [[Category: Protease]] | ||
| - | [[Category: Transmembrane]] | ||
| - | [[Category: Zymogen]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:23:40 2010'' | ||
Revision as of 05:57, 25 May 2011
Contents |
Fragment Based Discovery and Optimisation of BACE-1 Inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3msm is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
