3qrk

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'''Unreleased structure'''
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[[Image:3qrk.jpg|left|200px]]
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The entry 3qrk is ON HOLD
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{{STRUCTURE_3qrk| PDB=3qrk | SCENE= }}
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Authors: Chun, L., Flynn, D.L., Stewart, L.
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===The crystal structure of human abl1 kinase domain in complex with DP-987===
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Description: The crystal structure of human abl2 kinase domain in complex with DP-987
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{{ABSTRACT_PUBMED_21481795}}
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==About this Structure==
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[[3qrk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRK OCA].
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==Reference==
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<ref group="xtra">PMID:021481795</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Ahn, Y M.]]
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[[Category: Chan, W W.]]
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[[Category: Chun, L.]]
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[[Category: Clark, R.]]
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[[Category: Ensinger, C L.]]
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[[Category: Etten, R A.Van.]]
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[[Category: Evangelista, P.]]
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[[Category: Flynn, D L.]]
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[[Category: Gavrilescu, L C.]]
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[[Category: Haack, T.]]
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[[Category: Hood, M M.]]
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[[Category: Jones, J.]]
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[[Category: Kaufman, M D.]]
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[[Category: Lazarides, K.]]
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[[Category: Lord, J W.]]
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[[Category: Lu, W P.]]
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[[Category: Miller, D.]]
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[[Category: Patt, W C.]]
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[[Category: Petillo, P A.]]
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[[Category: Rutkoski, T J.]]
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[[Category: Smith, B D.]]
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[[Category: Stewart, L J.]]
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[[Category: Telikepalli, H.]]
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[[Category: Vogeti, L.]]
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[[Category: Wise, S C.]]
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[[Category: Yao, T.]]
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[[Category: Zaleskas, V M.]]

Revision as of 05:47, 1 June 2011

Template:STRUCTURE 3qrk

The crystal structure of human abl1 kinase domain in complex with DP-987

Template:ABSTRACT PUBMED 21481795

About this Structure

3qrk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chan WW, Wise SC, Kaufman MD, Ahn YM, Ensinger CL, Haack T, Hood MM, Jones J, Lord JW, Lu WP, Miller D, Patt WC, Smith BD, Petillo PA, Rutkoski TJ, Telikepalli H, Vogeti L, Yao T, Chun L, Clark R, Evangelista P, Gavrilescu LC, Lazarides K, Zaleskas VM, Stewart LJ, Van Etten RA, Flynn DL. Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036. Cancer Cell. 2011 Apr 12;19(4):556-68. PMID:21481795 doi:10.1016/j.ccr.2011.03.003

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