Factor VIII
From Proteopedia
(Difference between revisions)
(New page: Crystal Structure of human Factor VIII, 2r7e {{STRUCTURE_2r7e| PDB=2r7e | SIZE=300| SCENE= |right|CAPTION=Human Factor VIII, 2r7e }} [[Factor...) |
|||
| Line 1: | Line 1: | ||
[[Image:2r7e.png|left|200px|thumb|Crystal Structure of human Factor VIII, [[2r7e]]]] | [[Image:2r7e.png|left|200px|thumb|Crystal Structure of human Factor VIII, [[2r7e]]]] | ||
| - | {{STRUCTURE_2r7e| PDB=2r7e | SIZE=300| SCENE= |right|CAPTION=Human Factor VIII, [[2r7e]] }} | + | {{STRUCTURE_2r7e| PDB=2r7e | SIZE=300| SCENE=Factor_VIII/Cv/1 |right|CAPTION=Human Factor VIII, [[2r7e]] }} |
[[Factor VIII]] (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for factor IXa. The images at the left and at the right correspond to one representative FVIII, ''i.e.'' the crystal structure of chicken human Factor VIII ([[2r7e]]). | [[Factor VIII]] (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for factor IXa. The images at the left and at the right correspond to one representative FVIII, ''i.e.'' the crystal structure of chicken human Factor VIII ([[2r7e]]). | ||
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
| + | <br /> | ||
| + | <br /> | ||
| + | <br /> | ||
| + | <br /> | ||
| + | <br /> | ||
== 3D Structures of Factor VIII == | == 3D Structures of Factor VIII == | ||
Revision as of 08:41, 2 June 2011
Image:2r7e.png
Crystal Structure of human Factor VIII, 2r7e
Factor VIII (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for factor IXa. The images at the left and at the right correspond to one representative FVIII, i.e. the crystal structure of chicken human Factor VIII (2r7e).
Contents |
3D Structures of Factor VIII
2r7e, 3cdz – hFVIII – human
3hnb, 3hny, 3hob – hFVIII light chain C2 domain
1d7p - hFVIII light chain C2 domain (mutant)
1cfg, 1fac - hFVIII light chain C2 domain membrane-binding peptide - NMR
1iqd - hFVIII light chain C2 domain (mutant) + monoclonal Fab
