2djw

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Revision as of 17:04, 29 January 2008

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spinqualitylabelsall models 2djw, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Crystal structure of TTHA0845 from Thermus thermophilus HB8

Overview

The stand-alone RAM (regulation of amino-acid metabolism) domain protein, SraA from Thermus thermophilus HB8 (TTHA0845) was crystallized in the, presence of zinc ions. The X-ray crystal structure was determined using a, multiple-wavelength anomalous dispersion technique and was refined at 2.4, A resolution to a final R factor of 25.0%. The monomeric structure is a, betaalphabetabetaalphabeta fold and it dimerizes mainly through, interactions between the antiparallel beta-sheets. Furthermore, five SraA, dimers form a ring with external and internal diameters of 70 and 20 A, respectively. This decameric structure is unique compared with the, octameric and dodecameric structures found for other stand-alone, RAM-domain proteins and the C-terminal RAM domains of Lrp/AsnC-family, proteins.

About this Structure

2DJW is a Single protein structure of sequence from Thermus thermophilus with as ligand. Full crystallographic information is available from OCA.

Reference

Structure of the stand-alone RAM-domain protein from Thermus thermophilus HB8., Nakano N, Okazaki N, Satoh S, Takio K, Kuramitsu S, Shinkai A, Yokoyama S, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt, 9):855-60. Epub 2006 Aug 26. PMID:16946463

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