3r92

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
[[Image:3r92.jpg|left|200px]]
-
The entry 3r92 is ON HOLD until Paper Publication
+
<!--
 +
The line below this paragraph, containing "STRUCTURE_3r92", creates the "Structure Box" on the page.
 +
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 +
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 +
or leave the SCENE parameter empty for the default display.
 +
-->
 +
{{STRUCTURE_3r92| PDB=3r92 | SCENE= }}
-
Authors: Zapf, C.W., Bloom, J.D., McBean, J.L., Dushin, R.G., Golas, J.M., Liu, H., Lucas, J., Boschelli, F., Vogan, E.M., Levin, J.I.
+
===Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.===
-
Description: Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.
+
 
 +
<!--
 +
The line below this paragraph, {{ABSTRACT_PUBMED_21605975}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 21605975 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_21605975}}
 +
 
 +
==About this Structure==
 +
[[3r92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R92 OCA].
 +
 
 +
==Reference==
 +
<ref group="xtra">PMID:021605975</ref><references group="xtra"/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Bloom, J D.]]
 +
[[Category: Boschelli, F.]]
 +
[[Category: Dushin, R G.]]
 +
[[Category: Golas, J M.]]
 +
[[Category: Levin, J I.]]
 +
[[Category: Liu, H.]]
 +
[[Category: Lucas, J.]]
 +
[[Category: McBean, J L.]]
 +
[[Category: Vogan, E M.]]
 +
[[Category: Zapf, C W.]]

Revision as of 05:09, 8 June 2011

Image:3r92.jpg

Template:STRUCTURE 3r92

Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.

Template:ABSTRACT PUBMED 21605975

About this Structure

3r92 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zapf CW, Bloom JD, McBean JL, Dushin RG, Golas JM, Liu H, Lucas J, Boschelli F, Vogan E, Levin JI. Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3627-31. Epub 2011 Apr 28. PMID:21605975 doi:10.1016/j.bmcl.2011.04.102

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3r92"
Personal tools