3okj
From Proteopedia
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- | + | [[Image:3okj.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3okj", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
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+ | {{STRUCTURE_3okj| PDB=3okj | SCENE= }} | ||
- | + | ===Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition=== | |
- | + | ||
+ | ==About this Structure== | ||
+ | [[3okj]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKJ OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021154547</ref><references group="xtra"/> | ||
+ | [[Category: Proteasome endopeptidase complex]] | ||
+ | [[Category: Saccharomyces cerevisiae]] | ||
+ | [[Category: Gallastegui, P.]] | ||
+ | [[Category: Groll, M.]] | ||
+ | [[Category: Huber, R.]] | ||
+ | [[Category: Kloetzel, PM.]] | ||
+ | [[Category: Poynor, M.]] | ||
+ | [[Category: Schmidt, B.]] | ||
+ | [[Category: Stein, M.]] |
Revision as of 05:12, 8 June 2011
Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition
About this Structure
3okj is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Grawert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. Angew Chem Int Ed Engl. 2011 Jan 10;50(2):542-4. PMID:21154547 doi:10.1002/anie.201005488